Results 121 to 130 of about 562,355 (341)
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
A Liberal Enchanted by Socialism? The Issue of Ownership in Neoliberal Doctrine of Ferdinand Zweig
Ferdinand Zweig, who seems to be forgotten today, was one of the most eminent representatives of the so-called "Cracow School," an influential circle of economists associated with the Jagiellonian University.
Przemysław Pluciński +1 more
doaj
Port integration and competition under public and private ownership [PDF]
Lili Xu, Sang‐Ho Lee
openalex
The Separation of Ownership and Control in East Asian Corporations
S. Claessens +2 more
semanticscholar +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Data ownership is a contested topic in the European systems of private law. This contribution aims to provide a general overview of the current state of the debate on data ownership within the three major legal traditions in Europe: French law, German law, and English law.
openaire +1 more source
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source

