Results 71 to 80 of about 40,783 (304)

Ownership Concentration, Corporate Governance and Firm Performance: Evidence from Pakistan [PDF]

open access: yes
The study investigates the determinants of ownership concentration, the effect of ownership concentration on the firm’s performance with the sample of sixty representativ e firms from different manufacturing sectors of the Pakistan’s economy during 2003 ...
Attiya Y. Javid, Robina Iqbal
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Ownership Concentration and Performance in Ukraine's Privatized Enterprises [PDF]

open access: yes
This article investigates empirically the relationship between ownership concentration and performance in 376 partially and fully privatized Ukrainian enterprises. It finds that ownership concentration is positively associated with enterprise performance
Alexander Pivovarsky
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

The Ownership Concentration of Firms: Three Essays on the Determinants and Effects [PDF]

open access: yes
The question for the determinants and effects of the ownership concentration of firms is of central concern in the corporate governance literature. It has attracted significant attention in the last decades and has been frequently addressed by renown ...
Weiß, Christian
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

U-Shape Nonlinearity of Ownership Concentration on Firm Value

open access: yesJurnal Ekonomi Pendidikan dan Kewirausahaan, 2019
The ownership and value relationship of the company has a lot of contentious issues. Previous studies have only examined the linear effect of ownership concentration on company value.
Ahmad Aziz Putra Pratama
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Ownership concentration and market discipline in European banking: Good monitoring but bad influence? [PDF]

open access: yes
We investigate the impact of banks’ ownership concentration on the effectiveness of shareholders’ market discipline. More precisely, we first assess whether the ability of the distance to default to predict banks’ financial distress is affected by the ...
Tristan AUVRAY (LEREPS-GRES)   +1 more
core  

THE EFFECT OF OWNERSHIP STRUCTURE ON INTELLECTUAL CAPITAL AND ITS IMPACT ON COMPANY VALUE (A STUDY OF THE BANKING SECTOR ON THE INDONESIA STOCK EXCHANGE 2020-2024 PERIOD)

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study aims to analyze the influence of ownership structure, including institutional ownership, foreign ownership, and ownership concentration, on intellectual capital and its impact on firm value in the banking sector on the Indonesia Stock ...
Frans Atiaqsa, Jacobus Widiatmoko
doaj   +1 more source

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