Results 41 to 50 of about 20,917 (170)

Structural Modifications of Nonsteroidal Anti‐Inflammatory Drugs (NSAIDs): New Horizons in Antimicrobial Drug Discovery

Archiv der Pharmazie, Volume 359, Issue 8, August 2026.
This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan, Ayşe Karagüzel, Miyase Gözde Gündüz   +2 more
wiley   +1 more source

Antimicrobial Stewardship, Laboratory Surveillance, and Quality Management in Africa: A Narrative Review of Challenges and Opportunities for Integrated AMR Control

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Introduction Antimicrobial resistance (AMR) is a growing public health threat that disproportionately affects African countries due to high infectious disease burdens, widespread antimicrobial misuse, weak health systems, inadequate diagnostic capacity, and fragmented surveillance infrastructure.
Ameh Wisdom Owoicho, Majani Edward
wiley   +1 more source

Prevalence, Antimicrobial Resistance Profile, and Multidrug Resistance of Methicillin‐Resistant Staphylococcus aureus (MDR‐MRSA) in Clinical Isolates From Indonesian Healthcare Facility: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Methicillin‐resistant Staphylococcus aureus (MRSA) is a significant pathogen associated with hospital‐acquired infections, with its global prevalence, including in Indonesia, steadily increasing. However, comprehensive data on MRSA prevalence and antimicrobial susceptibility within Indonesian hospital settings remain ...
Muhammad Evy Prastiyanto, Afifah Khairunnisa, Shiv Kumar Sah   +2 more
wiley   +1 more source

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source

Biofilm-mediated antibiotic tolerance in Staphylococcus aureus from spinal cord stimulation device-related infections

Microbiology Spectrum
Staphylococcus aureus is a predominant cause of infections in individuals with spinal cord stimulation (SCS) devices. Biofilm formation complicates these infections, commonly requiring both surgical and antibiotic treatments.
Francesca Sivori, Ilaria Cavallo, Mauro Truglio, Lorella Pelagalli, Valerio Mariani, Giorgia Fabrizio, Elva Abril, Iolanda Santino, Piera Assunta Fradiani, Mariacarmela Solmone, Fulvia Pimpinelli, Luigi Toma, Roberto Arcioni, Roberto Alberto De Blasi, Enea Gino Di Domenico   +14 more
doaj   +1 more source

Role of ClpX and MsrA/B in the Oxidative and Cell Wall Stress Response in Bacillus anthracis Sterne

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Methionine sulfoxide reductase (msrA/B) is an oxidative response enzyme that reduces oxidized methionine residues to maintain protein function. Surprisingly, loss of MsrA/B does not increase sensitivity to hydrogen peroxide or paraquat‐induced oxidative stress in Bacillus anthracis Sterne.
Aeron B. Pennington, Salina Hona, Josey I. Austin, Kelsey C. Waite, Mikaela D. Stewart, Shauna M. McGillivray   +5 more
wiley   +1 more source

First Report of Oxacillin Susceptible mecA-Positive Staphylococcus aureus in a Children’s Hospital in Kunming, China

Infection and Drug Resistance, 2021
Mingbiao Ma,1– 3,* Minjun Chu,1,2,* Lvyan Tao,3– 5,* Jue Li,1,2 Xiaojuan Li,1,2 Hailin Huang,1,2 Kexuan Qu,6 Haiping Wang,1,2 Li Li,3– 5 Tingyi Du1– 3 1Department of Clinical Laboratory, Kunming Children’s Hospital, Kunming, Yunnan, People’s ...
Ma M, Chu M, Tao L, Li J, Li X, Huang H, Qu K, Wang H, Li L, Du T   +9 more
doaj  

Comparing clinical manifestations, treatment strategies and outcomes of Staphylococcus lugdunensis bacteraemia versus Staphylococcus aureus bacteraemia – a retrospective cohort study

Internal Medicine Journal, Volume 56, Issue 8, Page 1385-1393, August 2026.
Abstract Background Staphylococcus lugdunensis is a coagulase‐negative Staphylococcus that has been increasingly recognised as a significant pathogen capable of causing invasive infections similar to Staphylococcus aureus. Data comparing the clinical manifestations and outcomes of S. lugdunensis bacteraemia to S. aureus bacteraemia remain limited. This
Gemma Webb, Jasmine Choi, Angela Younes, Emily Schembri, Roy Chean, Stephen Guy   +5 more
wiley   +1 more source

Resistencia a oxacilina, eritromicina y gentamicina en cepas de Staphylococcus coagulasa negativa aisladas de hemocultivos

Kasmera, 2016
: Resistance to antimicrobials in Gram-positive bacteria such as coagulase negative Staphylococcus is an emerging global threat. The purpose of this research was to identify the genes for resistance to oxacillin (mecA), erythromycin (erm and msrA), and ...
Castellano-González Maribel, Perozo-Mena Armindo, Devis-Soto Raquel   +2 more
doaj  

Effect of a Point Mutation in mprF on Susceptibility to Daptomycin, Vancomycin, and Oxacillin in an MRSA Clinical Strain

Frontiers in Microbiology, 2018
We previously reported the sequential recovery of daptomycin-nonsusceptible MRSA clinical isolates with an L431F substitution in the MprF protein. The aim of the present study is to determine the effect of this mutation by replacing the mprF gene on the ...
Feng-Jui Chen, Tsai-Ling Lauderdale, Chen-Hsiang Lee, Yu-Chieh Hsu, I-Wen Huang, Pei-Chi Hsu, Chung-Shi Yang   +6 more
doaj   +1 more source