Results 91 to 100 of about 7,735 (257)
BACKGROUND & AIMS Many colorectal cancer (CRC) cells contain mutations in KRAS. Analyses of CRC cells with mutations in APC or CTNNB1 and KRAS identified SLC25A22, which encodes mitochondrial glutamate transporter, as a synthetic lethal gene.
C. Wong+16 more
semanticscholar +1 more source
Pyruvic and oxaloacetic cyanohydrins [PDF]
Stanley William Williamson+1 more
openaire +3 more sources
The multifaceted roles of ketones in physiology
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili+3 more
wiley +1 more source
A novel hydantoin synthesis and exploration of related reactions [PDF]
Chapter one gives a short history of the discovery of hydantoins, followed by their chemical properties and reactivity and concluding with the many ways to date that they have been synthesized.
Leonard, M
core
The oxaloacetate acetylhydrolase (OAH, EC 3.7.1.1)-encoding gene Ss-oah1 was cloned and functionally characterized from Sclerotinia sclerotiorum. Ss-oah1 transcript accumulation mirrored oxalic acid (OA) accumulation with neutral pH induction dependent ...
Xiaofei Liang+6 more
semanticscholar +1 more source
Abstract figure legend An integrated model of human ventricular myocyte with excitation‐contraction‐energetics coupling was created to systematically analyse the contribution of Ca2+ regulation of mitochondrial enzymes to cardiomyocyte functions during workload transition; i.e. exercise.
Ayako Takeuchi, Satoshi Matsuoka
wiley +1 more source
THE EQUILIBRIUM OF THE REACTION CATALYSED BY CITRATE OXALOACETATE-LYASE [PDF]
SS TATE, SP Datta
openalex +1 more source
The Role of TCA Cycle Anaplerosis in Ketosis and Fatty Liver in Periparturient Dairy Cows
The transition to lactation period in dairy cattle is characterized by metabolic challenges, negative energy balance, and adipose tissue mobilization. Metabolism of mobilized adipose tissue is part of the adaptive response to negative energy balance in ...
H. White
semanticscholar +1 more source
A sensitive method for estimation of oxaloacetate [PDF]
D. F. Tapley, G. Kalnitsky
openaire +3 more sources
Daily blood flow restriction does not preserve muscle mass and strength during 2 weeks of bed rest
Abstract figure legend Two weeks of bed rest lowers skeletal muscle mass and strength. Daily passive blood flow restriction during bed rest does not modulate daily muscle protein synthesis and does not preserve skeletal muscle mass or strength. Created with BioRender.com.
Cas J. Fuchs+10 more
wiley +1 more source