Results 1 to 10 of about 69 (69)
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source
Experimental and Theoretical Studies of Dissociative Electron Attachment to Metabolites Oxaloacetic and Citric Acids [PDF]
International Journal of Molecular Sciences, 2021 In this contribution the dissociative electron attachment to metabolites found in aerobic organisms, namely oxaloacetic and citric acids, was studied both experimentally by means of a crossed-beam setup and theoretically through density functional theory calculations.
Kopyra, Janina +6 more
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The Enzymic Conversion of the Tartaric Acids to Oxaloacetic Acid [PDF]
Journal of General Microbiology, 1957 SUMMARY: Certain bacteria of the genus Pseudomonas attack the tartaric acids by means of inducible stereospecific dehydrases. Each dehydrase converts its specific isomeric substrate to oxaloacetic acid; in crude cell-free extracts the oxaloacetic acid is in turn converted to pyruvic acid, which accumulates.
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Catalytic oxidative dehydrogenation of malic acid to oxaloacetic acid
Green Chemistry, 2019 Here we report the oxidative dehydrogenation of malic acid to oxaloacetic acid, a key precursor in the fabrication of amino acids, over Pt–Bi/C catalysts.
Drif, Asmaa +5 more
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Energetics of the Citric Acid Cycle in the Deep Biosphere
Geophysical Monograph Series, Page 303-327., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Peter A. Canovas III, Everett L. Shock
wiley +1 more source
Oxaloacetic Acid Supplementation as a Mimic of Calorie Restriction [PDF]
Open Longevity Science (Formerly 'The Open Aging Journal'), 2009 The reduction in dietary intake leads to changes in metabolism and gene expression that increase lifespan, re- duce the incidence of heart disease, kidney disease, Alzheimer's disease, type-2 diabetes and cancer. While all the mo- lecular pathways which result in extended lifespan as a result of calorie restriction are not fully understood, some of ...
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Hepatic gluconeogenesis and regulatory mechanisms in lactating ruminants: A literature review
Animal Research and One Health, EarlyView.phosphoenolpyruvate carboxy kinase, FBP1, and glucose‐6‐phosphatase are key rate‐limiting enzymes that determine the efficiency of gluconeogenesis. The main substrate for gluconeogenesis in the liver of ruminants is propionate, which provides more than 60% of the carbon source for gluconeogenesis.
Guoyan Wang +5 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract One strategy to enhance the production of biological therapeutics is using transient perfusion in the preculture (N‐1 stage) to seed the production culture (N stage) at ultra‐high cell densities (>10 x 106 viable cells/mL). This very high seeding density improves cell culture performance by shortening the timeline and/or achieving higher final
Lucas Lemire +5 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger +15 more
wiley +1 more source
Food Frontiers, EarlyView.Nutraceutical Potential in Disease Mitigation and Health Enhancement of Actinidia spp. (Kiwifruit) ABSTRACT This review offers an in‐depth exploration of the Actinidia species (kiwifruit) nutritional composition, the pivotal role of its primary bioactive compounds, and their potential applications across the aforementioned health concerns. Furthermore,
Allah Rakha +7 more
wiley +1 more source