Results 151 to 160 of about 2,441 (215)

GC-MS/MS and HR-LCMS-QTOF analysis of various extracts of Saraswata Ghrita: A comprehensive dataset on phytochemical compounds. [PDF]

Data Brief
Badal R, Ranjan S, Jha SK, Kumar L, Patel AK, Yadav P, Prajapati PK.   +6 more
europepmc   +1 more source

Contribution of parasite and host genotype to immunopathology of schistosome infections. [PDF]

Parasit Vectors
Jutzeler KS, Le Clec'h W, Chevalier FD, Anderson TJC.   +3 more
europepmc   +1 more source

The application of chemical similarity measures in an unconventional modeling framework c-RASAR along with dimensionality reduction techniques to a representative hepatotoxicity dataset. [PDF]

Sci Rep
Banerjee A, Roy K.
europepmc   +1 more source

Chemoprophylactic properties of oxamniquine embonate in experimental schistosomiasis.

Revista do Instituto de Medicina Tropical de Sao Paulo, 1980
Korolkovas, Andrejus, Coelho, Paulo Marcos Zech, Rocha, Miriam Oliveira e, Pereira, Leógenes Horácio, Barbosa, Maria Aparecida   +4 more
openaire   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Studies on the mode of action of oxamniquine and related schistosomicidal drugs.

The American Journal of Tropical Medicine and Hygiene, 1985
Adult Schistosoma mansoni were incubated for 1 hour in vitro with various drugs and then returned into the mesenteric veins of permissive animal hosts. Survival of schistosomes was assessed 3-4 weeks later by portal perfusion.
L. Pica-Mattoccia, D. Cioli
semanticscholar   +3 more sources

Medicinal chemistry of antischistosomal drugs: Praziquantel and oxamniquine.

Bioorganic & Medicinal Chemistry, 2017
Neglected tropical diseases (NTDs) are a group of diseases that, besides prevailing in poverty conditions, contribute to the maintenance of social inequality, being a strong barrier to a country development. Schistosomiasis, a NTD, is a tropical and subtropical disease caused by the trematode Schistosoma mansoni (Africa, Middle East, Caribbean, Brazil,
V. D. da Silva, Bruna Rafaella Koresch Leiva Campos, J. F. de Oliveira, J. Décout, Maria do Carmo Alves de Lima   +4 more
semanticscholar   +4 more sources

Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as Novel Drug Candidates for Schistosomiasis.

Chemistry, 2020
Schistosomiasis is a disease of poverty affecting millions of people. Praziquantel (PZQ), with its strengths and weaknesses, is the only treatment available.
Valentin Buchter, Y. C. Ong, François Mouvet, Abdallah Ladaycia, E. Lepeltier, U. Rothlisberger, J. Keiser, G. Gasser   +7 more
semanticscholar   +1 more source

Determination of Oxamniquine in Serum

Journal of Pharmaceutical Sciences, 1977
A method for the analysis of oxamniquine in serum (or plasma), sensitive to 10 ng/ml, was developed. Oxamniquine and a close structural analog as the internal standard were extracted from serum with ether. After derivatization with N,O-bis(trimethylsilyl)acetamide, oxamniquine was determined as its trimethylsilyl ether derivative by GLC using an ...
N.M. Woolhouse, P.R. Wood
openaire   +2 more sources

Binding of oxamniquine to the DNA of schistosomes

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1989
Hycanthone-sensitive and hycanthone-resistant schistosomes (which are also sensitive and resistant to oxamniquine) were exposed in vitro to tritium-labelled oxamniquine. The initial uptake of the drug into the schistosomes was essentially the same for the 2 strains.
S. Archer, L. Pica-Mattoccia, Donato Cioli   +2 more
openaire   +3 more sources

The metabolism of oxamniquine—a new schistosomicide

Annals of Tropical Medicine & Parasitology, 1976
The metabolism of oxamniquine, 6-hydroxymethyl-7-nitro-2-isopropylaminomethyl-1,2,3,4-tetrahydroquinoline, has been studied in the mouse, rat, hamster, rabbit, rhesus monkey, dog and man. Urinary excretion is a major route of elimination in man. The compound is converted to two metabolites, the major one arising from oxidation of the 6-hydroxymethyl ...
N. M. Woolhouse, B. Kaye
openaire   +3 more sources