Results 151 to 160 of about 13,823,125 (339)

Prolonged stress-induced depression-like behaviors in aged rats are mediated by endoplasmic reticulum stress and apoptosis in the hippocampus

Neuroscience Research
Structural and functional recovery from stress-induced depression is impaired in the context of aging brain. Since investigating the molecular substrates that facilitate behavioral recovery may have important implications for understanding brain ...
Arshad Ghaffari-Nasab, Gonja Javani, Hadi Yousefi, Rahim Sharafkhani, Sajjad Taghizadeh   +4 more
doaj  

Rectal mucosal quantitative galactose oxidase-Schiff reaction as an early detection biomarker for colorectal cancer: Comparison to fecal occult stool blood test [PDF]

, 2011
Mack T. Ruffin, Daniel P. Normolle, M. J. Evelegh, John A. Baron, Robert S. Bresalier, Norman E. Marcon, Sapna Syngal, D. Kim Turgeon, Melissa Tuck, Dean E. Brenner   +9 more
openalex   +1 more source

Harnessing Synergistic Cooperation of Neighboring Active Motifs in Heterogeneous Catalysts for Enhanced Catalytic Performance

Advanced Materials, EarlyView.
This review examines the critical role of neighboring active motifs in heterogeneous catalysts, emphasizing how their synergistic cooperativity can be rationally designed to modulate catalytic properties. The discussion centers on the modulation of electronic and geometric structures, categorizing the catalytic systems into metal‐acid (Brønsted/Lewis ...
Peng Yuan, Ching Kit Tommy Wun, Tsz Woon Benedict Lo   +2 more
wiley   +1 more source

Bioinspired Design of Heterogenous Single‐Atomic‐Site Catalysts for Electrocatalysis and Photocatalysis

Advanced Materials, EarlyView.
This review gives a summary on the representative bioinspired single‐atomic‐site catalysts (SACs) and their applications in heterogeneous electrocatalysis and photocatalysis. The fundamentals of bioinspired design strategies are systematically discussed in the context of the first shell coordination, the second/long‐range coordination, and the outer ...
Ying Wang, Guangri Jia, Piaoping Yang, Linshan Zhang, Kwok‐Yin Wong   +4 more
wiley   +1 more source

Behavioral and Biochemical Evidences for Antidepressant-Like Activity of Celastrus Paniculatus Seed Oil in Mice

Basic and Clinical Neuroscience, 2016
Introduction: Celastrus paniculatus seed oil, commonly known as Malkangni or Jyotishmati, was in use from time immemorial to treat brain related disorders.
Rekha Valecha, Dinesh Dhingra
doaj  

Organic AIE Nanoradiosensitizer Potentiates X‐Ray Triggered Continuous Reactive Oxygen Species Generation for Potent Cancer Radioimmunotherapy

Advanced Materials, EarlyView.
Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu, Minmin Zhang, Qinqin Huang, Song Gao, Sitong Chu, Qi Li, Wanyao Chen, Xinglong Zhang, Tianfu Zhang, Ben Zhong Tang, Shipeng Ning   +10 more
wiley   +1 more source

β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase [PDF]

, 2004
β-Amyloid (βA) peptide is strongly implicated in the neurodegeneration underlying Alzheimer's disease, but the mechanisms of neurotoxicity remain controversial. This study establishes a central role for oxidative stress by the activation of NADPH oxidase
Abramov, A.Y., Canevari, L., Duchen, M.R.   +2 more
core  

The Role of Artificial Intelligence in Advancing Biosensor Technology: Past, Present, and Future Perspectives

Advanced Materials, EarlyView.
This review explores the transformative role of AI in biosensor technology and provides a holistic interdisciplinary perspective that covers a broader scope of AI‐enabled biosensor technologies across various sectors including healthcare, environmental monitoring, food safety, and agriculture. It also highlights the important role of novel materials in
Tuğba Akkaş, Mahshid Reshadsedghi, Mustafa Şen, Volkan Kılıç, Nesrin Horzum   +4 more
wiley   +1 more source

Identification of the alternative oxidase gene and its expression in the copepod Tigriopus californicus [PDF]

, 2019
In addition to the typical electron transport system (ETS) in animal mitochondria responsible for oxidative phosphorylation, in some species there exists an alternative oxidase (AOX) pathway capable of catalyzing the oxidation of ubiquinol and the ...
Cygelfarb, Willie, McDonald, Allison, Singh, Jaspreet, Tward, Carly E.   +3 more
core   +1 more source

Spatial Coordination Structure‐Driven Enzyme‐Like Selectivity in Single‐Atom Nanozymes

Advanced Materials, EarlyView.
Sun et al. reviews recent progress in enhancing the enzyme‐like catalytic selectivity of SAzymes through the rational design of their spatial coordination structures. They emphasize the structure‐activity relationships of various attributes of these coordination structures in promoting selective catalytic behavior, the strategic design of coordination ...
Qijun Sun, Si Liu, Ziping Li, Peiji Deng, Na Niu, Ligang Chen, Kang Liang   +6 more
wiley   +1 more source