Results 161 to 170 of about 13,823,125 (339)

PEGylated porcine–human recombinant uricase: A novel fusion protein with improved efficacy and safety for the treatment of hyperuricemia and renal complications

Open Life Sciences
The growing prevalence of hyperuricemia necessitates the urgent development of more potent treatments. This study aimed to develop, optimize, and evaluate the safety and efficacy of porcine–human recombinant uricase (PHRU) both in vitro and in vivo.
Wang Xiangyan, Lu Hao, Rong Jun, Sun Zhongjie, Zheng Yanhua, Fan Bolin, Jia Ziming   +6 more
doaj   +1 more source

Functionalized Antifouling Polymer Brushes for Biospecific Surfaces

Advanced Materials Interfaces, EarlyView.
Modern biosensors offer high sensitivity but often struggle with long‐term stability and selectivity for specific targets. Antifouling polymer brushes help enhance both stability and selectivity. In this review, we compare recent antifouling coatings, their design parameters, and how they are integrated with biorecognition elements for improved ...
Erik J. Postma, Luc Scheres, Sissi de Beer, Andriy R. Kuzmyn, Han Zuilhof   +4 more
wiley   +1 more source

Surface Engineering of Thrombus‐Targeting Nanocarriers for Cardiovascular Diseases: A Short Review

Advanced Materials Interfaces, EarlyView.
This paper systematically introduces surface modification strategies for thrombus‐targeting nanocarriers, highlights the clinical significance of nanocarrier‐based thrombolysis therapies, and prospects the synergy of combing thrombolysis and anti‐inflammatory therapies for enhanced therapeutic effect.
Xinyue Ge, Lei Ding, Wenjun Zhao, Bohan Cui, Xiang Guan, Mingfei Pan, Qingguo Li, Ning Gu   +7 more
wiley   +1 more source

Differentiation of Clostridium difficile, Clostridium bifermentans, Clostridium sordellii, and Clostridium perfringens from Diarrheal Stool by API ZYM and API LRA Oxidase Test [PDF]

, 1995
Carla Fontana, Teresa Jezzi, Gian Piero Testore, B Dainelli   +3 more
openalex   +1 more source

High‐Performance Black Phosphorus/Graphitic Carbon Nitride Heterostructure‐Based Wearable Sensor for Real‐time Sweat Glucose Monitoring

Advanced Materials Technologies, EarlyView.
This work introduces a BP‐gCN heterostructure‐based wearable glucose sensor designed for continuous, non‐invasive glucose monitoring. By enhancing electrochemical glucose oxidation, the sensor exhibits improved sensitivity and stability. The integration of DFT calculations and experimental results demonstrates the superior electrocatalytic performance ...
Ecem Ezgi Özkahraman, Zafer Eroğlu, Vladimir Efremov, Arooba Maryyam, Taher Abbasiasl, Ritu Das, Hadi Mirzajani, Berna Akgenc Hanedar, Levent Beker, Onder Metin   +9 more
wiley   +1 more source

Evaluation of NADPH Oxidase (NOX) Activity by nitro Blue Tetrazolium (NBT) Test in SLE Patients

, 2023
Ritasman Baisya, Shiva Krishna Katkam, Sreejitha KS, Phani Kumar Devarasetti, Vijay Kumar Kutala, Liza Rajasekhar   +5 more
openalex   +1 more source

Enzymatic Synthesis of Enantiopure (R)‐Citronellal from Geraniol via a Short‐Chain Dehydrogenase and Ene Reductase

Advanced Synthesis &Catalysis, EarlyView.
A synthetic cascade with two consecutive biocatalytic steps consisting of a short‐chain alcohol dehydrogenase and an ene reductase in a biphasic system provides (R)‐citronellal with >90% conversion and >99% enantiomeric excess from inexpensive geraniol. The development of synthetic routes to produce enantiopure (R)‐citronellal as a key intermediate for
Claudia Ferrer‐Carbonell, Rocio Villa, Iris Viskaal, Diederik J. Opperman, Caroline E. Paul   +4 more
wiley   +1 more source

Clinical and Experimental Applications of NIR-LED Photobiomodulation [PDF]

, 2006
This review presents current research on the use of far-red to near-infrared (NIR) light treatment in various in vitro and in vivo models. Low-intensity light therapy, commonly referred to as “photobiomodulation,” uses light in the far-red to near ...
Buchmann, Ellen V., Connelly, Mary P., Corry, Jesse J., Das, Rina, Desmet, Kristina D., Dovi, Julia V., Eells, Janis T., Gould, Lisa J., Henry, Michele M., Henshel, Diane S., Hodgson, Brian D., Jett, Marti, Liang, Huan Ling, Lim, Jinhwan, Margolis, David, Millsap, Deborah S., Paz, David A., Whelan, Harry T., Wong-Riley, Margaret T. T., Yeager, Ronnie L.   +19 more
core   +1 more source

Integrating Visible‐Light Photocatalysis and Enzymes for the Stereoselective Synthesis of Alcohols and Amines

Advanced Synthesis &Catalysis, EarlyView.
The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley   +1 more source

The peripheral leukocytes function test of cytochrome c oxidase deficiency.

, 1988
Teiichi Matsunaga, Kazuo Suzuki, Yasutoshi Koga, Ikuya Nonaka, Masashi Yamaguchi, Yukikatsu Ochiai, Yuki Yamazaki, Shigenobu Tsuzura, Satoshi Mizuno, Naoko Maekawa, Kihei Maekawa   +10 more
openalex   +2 more sources