Results 241 to 250 of about 13,917,494 (361)

Emerging Nanotechnology Strategies for Obesity Therapy

Advanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang, Zhaoxu Meng, Yuezhu Zhao, Yake Qi, Zhou Li, He Lian   +5 more
wiley   +1 more source

Dietary Supplementation of Novel Aflatoxin Oxidase CotA Alleviates Aflatoxin B₁-Induced Oxidative Stress, Lipid Metabolism Disorder, and Apoptosis in the Liver of Japanese Quails. [PDF]

Animals (Basel)
Lv H, Rao Z, Li Y, Zhang W, Zhao L, Wang Z, Guo Y.   +6 more
europepmc   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

Advanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen, YuWei Zhou, LongXiang Sheng, FangYing Mai, YuXuan Ding, ShiRan Hong, JiaXin Wu, JiaKai Pi, GuangMei Yan, YiJun Huang, JingJing Duan, Xuefeng Hua, Wei Yin   +12 more
wiley   +1 more source

Carbonsulfan-induced physiological, histopathological, and ultrastructural alterations in tubifex tubifex (müller, 1774). [PDF]

Sci Rep
Mandal AH, Sadhu A, Ghosh S, Saha NC, Saha S.   +4 more
europepmc   +1 more source

NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia.

Antioxidants and Redox Signaling, 2013
Justine M. Abais, Chun Zhang, M. Xia, Qinglian Liu, T. Gehr, K. Boini, Pin-Lan Li   +6 more
semanticscholar   +1 more source

Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy

Advanced Science, EarlyView.
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao, Xianping Liu, Xu Chu, Feixiang Chen, Ruicheng Shi, Zonghao Liu, Yelin Wu, Yanyan Liu, Wenbo Bu   +8 more
wiley   +1 more source

Safety evaluation of the food enzyme glucose oxidase from the non-genetically modified <i>Aspergillus tubingensis</i> strain GOX. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Aguilera J, Andryszkiewicz M, Pesce F, Marini E, Criado A, Liu Y.   +19 more
europepmc   +1 more source

NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus

Science Translational Medicine, 2012
Allison M. Campbell, M. Kashgarian, M. Shlomchik   +2 more
semanticscholar   +1 more source

Bacteria Optimize Tumble Bias to Strategically Navigate Surface Constraints

Advanced Science, EarlyView.
The study investigates how Escherichia coli optimizes tumble bias (TB) to navigate surface constraints effectively. Using single‐cell tracking and modeling, it reveals that bacterial surface residence time decreases with increasing TB, stabilizing near the wild‐type mean TB (≈0.25), where surface diffusivity peaks.
Antai Tao, Guangzhe Liu, Rongjing Zhang, Junhua Yuan   +3 more
wiley   +1 more source

Khaya grandifololia exerts multitarget neuroprotective potential against neurodegenerative disorders: In vitro and in silico studies. [PDF]

IBRO Neurosci Rep
Ella FA, Ambamba BDA, Njayou FN, Moundipa PF.   +3 more
europepmc   +1 more source