Results 241 to 250 of about 14,319,230 (341)

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

Ten novel psychrophilic <i>Flavobacterium</i> species from Tibetan Plateau glaciers define a cryospheric lineage with global cold-origin relatives. [PDF]

Int J Syst Evol Microbiol
Liu Q, Yang LL, Xin YH.
europepmc   +1 more source

NADPH oxidase-derived reactive oxygen species contribute to impaired cutaneous microvascular function in chronic kidney disease.

AJP - Renal Physiology, 2014
Jennifer J DuPont, M. Ramick, W. Farquhar, R. Townsend, D. Edwards   +4 more
semanticscholar   +1 more source

Iron/Cobalt Dual‐Atom Catalyst Orchestrate Photothermal‐Chemodynamic Immunotherapy Against MRSA: Multi‐Omics Dissection in Murine and Porcine Models

Advanced Science, EarlyView.
FeCo dual‐atom catalyst (FeCo‐N‐DAC) with ultrahigh metal loading (Fe > 5.4%, Co > 4.8%) is developed for synergistic photothermal‐chemodynamic immunotherapy. FeCo‐N‐DAC penetrates deep‐seated tissues, eradicates MRSA biofilms, and reprograms immune‐inflammatory pathways via multi‐omics‐validated mechanisms.
Shihao Xu, Binge Huang, Hao Lin, Jinming Li, Zhaoxiang Lu, Qi Zhang, Jia Li, Shiping Yang, Songsong Lan, Yan Yang, Yun Feng, Xiaojun He   +11 more
wiley   +1 more source

Differentiation of parasitic and saprophytic leptospirae by oxidase test A hasty modus operandi

, 2009
Nagarajan Prabhu, Sivasamy Senthil Prabhu, Mohammed Thanveer, Revathi Nagarajan, Narayanan Josna, Rajaputhran Darsana, Danialas Joseph Pushpa Innocent, Chinnaswamy Palaniswamy   +7 more
openalex   +2 more sources

Mussel‐Bioinspired Edible Ca2+‐Crosslinked Alginate Hydrogel Electrodes for Glucose Gastrointestinal Monitoring

Advanced Science, EarlyView.
A fully edible soft electrode is engineered from Ca2⁺‐crosslinked alginate integrated with polydopamine, silver nanoparticles, and food‐grade glucose oxidase. The hybrid hydrogel combines ionic and electronic conduction, enabling efficient glucose‐to‐H2O2 conversion and catalytic reduction in simulated intestinal fluid.
Verdiana Marchianò, Claudio Pellegrini, Angelo Tricase, Eleonora Macchia, Andrea Brattelli, Luigi Gentile, Patrizia Nadia Hanieh, Noemi Fiaschini, Antonio Rinaldi, Luisa Torsi, Paolo Bollella   +10 more
wiley   +1 more source

Bimetallic Ti₃C₂T _<i>x</i> with three synergistic catalytic pathways and enhanced dual enzyme activities for a visual sensing platform. [PDF]

Nanoscale Adv
Zhou Z, Zou L, Zhang P, Dong J, Zhou J, Jiang H, Ren H, Li Z, Niu H, Liao H, Zhang X, An S, Ren F, Ge X, Cheng L, Yang F, Pan H, Rong S, Ma H.   +18 more
europepmc   +1 more source

NADPH Oxidase-Mediated Triggering of Inflammasome Activation in Mouse Podocytes and Glomeruli During Hyperhomocysteinemia

Antioxidants and Redox Signaling, 2013
Justine M. Abais, Chun Zhang, M. Xia, Qinglian Liu, T. Gehr, K. Boini, Pin-Lan Li   +6 more
semanticscholar   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Neurochemical metabolic pathways display regional and age-specific expression patterns in the chicken intestinal tract. [PDF]

Poult Sci
Wickramasuriya SS, Lyte JM.
europepmc   +1 more source