Results 261 to 270 of about 13,823,125 (339)

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

open access: yesAdvanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye   +13 more
wiley   +1 more source

A Needle‐Like H2S‐Releasing and H2O2 Self‐Replenishing Nanoplatform for Enhanced Chemodynamic Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
The PTA‐SnS2@GOx cascade nanosystem presents a smart paradigm for cancer theranostics, integrating self‐supplied H2S/H2O2‐augmented chemodynamic therapy (CDT) with sensitized immunotherapy. Its needle‐like SnS2 shell enhances tumor‐specific uptake, ensuring biosafety.
Xiaoxiao Sun   +3 more
wiley   +1 more source

Pathogenicity of Streptomyces scabies and identification of tolerant potato cultivars for scab-prone regions. [PDF]

open access: yesBMC Plant Biol
Ghuffar S   +7 more
europepmc   +1 more source

Sweat Wearable Sensor Based on Confined Pt Nanoparticles in 2D Conductive Metal–Organic Frameworks for Continuous Glucose Monitoring

open access: yesAdvanced Science, EarlyView.
An integrated wearable system is developed for nonenzymatic sweat glucose monitoring at the point of care. The system couples a microfluidic patch based on Pt nanoparticles confined in phthalocyanine‐based conductive MOFs with a flexible wireless circuit.
Wei Huang   +4 more
wiley   +1 more source

Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications

open access: yesAdvanced Electronic Materials, EarlyView.
This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster   +2 more
wiley   +1 more source

Modification of the rapid antimicrobial susceptibility testing from blood culture protocol for a resource-limited setting. [PDF]

open access: yesJAC Antimicrob Resist
Imwattana K   +5 more
europepmc   +1 more source

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

open access: yesAggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky   +3 more
wiley   +1 more source

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