Results 271 to 280 of about 14,319,230 (341)

The free fatty acid 2 receptor regulates the activation potency of C5a and the sensitivity to the antagonist avacopan

Khan Z, Levin NK, Dahlgren C, Sundqvist M, Khan F, Forsman H, Björkman L.   +6 more
europepmc   +1 more source

Evidence for ethanol-dependent acetic acid resistance in <i>Acetobacter pasteurianus</i> strain SKU1108. [PDF]

Appl Environ Microbiol
Narimatsu A, Murakami K, Kataoka N, Yamashita R, Matsushita K, Matsutani M, Tippayasak U, Theeragool G, Yakushi T.   +8 more
europepmc   +1 more source

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding, Zhongxiong Fan, Guoyu Xia, Fukai Zhu, Nan Yang, Shujie Yu, Longlong Yuan, Jinyao Li   +7 more
wiley   +1 more source

Oral KDS2010, a Monoamine Oxidase-B (MAO-B) Inhibitor, Slows the Deterioration of Motor Coordination in Genetic SCA1 Models by Inhibiting Astrocytic MAO-B-Mediated Inflammation. [PDF]

J Neurochem
Woo DH, Jeon JH, Ryu HJ, Lee GM, Lim HW, Park KD, Hoe KL, Rhee SD.   +7 more
europepmc   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

CircRNA-encoded protein fine-tunes ROS homeostasis and engages conserved JAK-STAT antiviral defenses in <i>Drosophila</i>. [PDF]

J Virol
Guo D, Xu W, Zhang L, Cui T, Tang L, Wu Q.   +5 more
europepmc   +1 more source

Efficient Preservation of Perishable Fruits by Erasable Metal‐Organic Frameworks

Advanced Science, EarlyView.
This study presents an erasable Pickering emulsion‐based coating stabilized by metal‐organic frameworks. This washable coating significantly extends fruit shelf life by scavenging ethylene and inhibiting foodborne pathogens, offering a sustainable solution for postharvest.
Liying Yang, Jia Kong, Haoran Bai, Xiaojie Wu, Douxin Xiao, Ming Du, Peng Yang, Alideertu Dong   +7 more
wiley   +1 more source

Histopathological modifications and biochemical defense responses of muskmelon (Cucumis Melo L.) to root-knot nematode (Meloidogyne incognita). [PDF]

Sci Rep
Basavaraj V, Sharada MS, Sampathkumar MR, Mahesh HM, Shanthi A.   +4 more
europepmc   +1 more source

Ce‐Doped Lignin‐Based Nanozyme with Heat‐Activated Hydrolase Activity

Advanced Science, EarlyView.
A novel Ce‐doped lignin‐based hydrolase nanozyme (Ce‐AL) is synthesized using Ce ions coordinated with aminated industrial lignin. The Ce‐AL effectively hydrolyzes phosphate ester bonds and protein amide bonds, maintain high activity at 100°C, and successfully fights bacteria biofilms.
Xin Liu, Lijun Li, Xue Zhang, Alireza Ashori, Fubao Sun, Feng Xu, Xueming Zhang, Yao Chen   +7 more
wiley   +1 more source

Unveiling potent xanthine oxidase inhibitors in two Balanophora spp. using machine learning-based virtual screening and molecular docking approach. [PDF]

Sci Rep
An NN, Tung DQ, Van Tue L, Son NT, Tung NT, Le HG, Tam TC, Thuan NT, Baecker D, Dung DTM.   +9 more
europepmc   +1 more source