Results 291 to 300 of about 587,820 (334)

Severe myelosuppression and alopecia after thiopurine initiation in a patient with NUDT15 deficiency

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Thiopurines are a class of immunosuppressant and antineoplastic agents. They are widely used in the treatment of inflammatory bowel disease, haematological malignancies and autoimmune diseases, but can cause significant toxicity. Inherited gene mutations are now recognized as independent risk factors for severe adverse drug reactions to thiopurines ...
Annie Siyu Wu   +3 more
wiley   +1 more source

The role of 1-Deoxysphingolipids and Polyamines in the pathogenesis of placental syndrome. [PDF]

open access: yesBMC Pregnancy Childbirth
Guleroglu FY   +10 more
europepmc   +1 more source

Use of Whole Cells and Cell‐Free Extracts of Catalase‐Deficient E. coli for Peroxygenase‐Catalyzed Reactions

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Unspecific peroxygenases (UPOs) and cytochrome P450 monooxygenases (CYPs) with peroxygenase activity are becoming the preferred biocatalysts for oxyfunctionalization reactions. While whole cells (WCs) or cell‐free extracts (CFEs) of Escherichia coli are often preferred for cofactor‐dependent monooxygenase reactions, hydrogen peroxide (H2O2 ...
Ana C. Ebrecht   +5 more
wiley   +1 more source

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