Results 311 to 320 of about 14,049,097 (359)
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Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile.

Journal of Medicinal Chemistry, 2018
Contilisant, a permeable, antioxidant, and neuroprotectant agent, showing high nM affinity at H3R and excellent inhibition of the monoamine oxidases and cholinesterases, is an affine and selective S1R agonist in the nanomolar range, based on the binding ...
Óscar M. Bautista-Aguilera   +9 more
semanticscholar   +1 more source

THE EFFECT OF MONOAMINE OXIDASE INHIBITORS ON GROWTH AND THE RAT TIBIA TEST

Journal of Endocrinology, 1965
SUMMARY A large number of monoamine oxidase (MAO) inhibitors: pivhydrazine (Tersavide), nialamide (Niamide), isocarboxazid (Marplan), mebanazine (Actomol), phenelzine (Nardil), pheniprazine (Catron) and tranylcypromine (Parnate), decrease cartilage growth in normal rats. This inhibition is not directly due to their properties as MAO inhibitors.
F. G. Sulman, U. Zor, S. Dikstein
openaire   +3 more sources

Serum Xanthine Oxidase: A Sensitive Test of Acute Liver Injury

Gastroenterology, 1965
Summary A sensitive assay for xanthine oxidase developed in our laboratory was used for the determination of the serum level of this enzyme (SeXO) in healthy subjects as well as in patients with various clinical disorders. In patients with viral hepatitis there was a marked elevation of SeXO (300 to 2800 times the upper limit of normal) during the ...
Munir H. Shamma'a   +4 more
openaire   +3 more sources

An in Vivo Test for Measuring Monoamine Oxidase Inhibition in Human Subjects

Archives of General Psychiatry, 1960
Previous work in this laboratory 1-5 has shown that when epinephrine labeled with C 14 in the N-methyl group of the side-chain was infused, approximately one-third of the radioactivity was recovered in the urine. These data suggested the following conclusions: (1) Approximately two-thirds of the infused epinephrine lose the N-methyl group of the side ...
H. Hoagland   +3 more
openaire   +3 more sources

Supplementary biochemical tests useful for the differentiation of oxidase positive staphylococci

Systematic and Applied Microbiology, 2007
Differentiation of the oxidase positive staphylococci, Staphylococcus sciuri, Staphylococcus lentus, Staphylococcus vitulinus and Staphylococcus fleurettii, based on tributyrin, urease, caseinase, gelatinase and DNase activity is described. These tests may be used for preliminary identification of oxidase positive isolates of staphylococci resulting in
Ivana Cirkovic   +7 more
openaire   +3 more sources

Discovery of novel secreted fungal sulfhydryl oxidases with a plate test screen

Applied Microbiology and Biotechnology, 2013
Sulfhydryl oxidases (SOX) are FAD-dependent enzymes capable of oxidising free thiol groups and forming disulphide bonds. Although the quantity of scientific papers and suggested applications for SOX is constantly increasing, only a limited number of microbial SOX have been reported and are commercially available.
Greta Faccio   +6 more
openaire   +4 more sources

A one-minute oxidase test to detect Vibrio strains isolated from cultures on thiosulphate-citrate-bile salts-sucrose (TCBS) medium.

Journal of Applied Bacteriology, 1992
J. Vila   +5 more
semanticscholar   +1 more source

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