Results 141 to 150 of about 2,387,776 (259)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Spectro-kinetic modelling of photocatalytic oxidation of heterocyclic compounds in a continuous-flow packed bed reactor. [PDF]

RSC Adv
Pal R, Farnood R.
europepmc   +1 more source

Stress Rupture Behavior of Silicon Carbide Coated, Low Modulus Carbon/Carbon Composites [PDF]

The disadvantages of carbon-carbon composites, in addition to the oxidation problem, are low thermal expansion, expensive fabrication procedures, and poor off axis properties.
Rozak, Gary A., Wallace, John F.
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

High-Temperature Isothermal Oxidation Behavior of Newly Developed Fe-Cr-Ni Austenite Stainless Steel. [PDF]

Materials (Basel)
Husain MN, Muniyandi T, Balaguru B, Amirtharaj Mosas KK, Chandrasekar AR, Devarajan DK.   +5 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Comparison of Oxide Scale Morphology on FeAl-Based Alloy After Long-Term Oxidation in Air and Water Vapor at 700 °C. [PDF]

Materials (Basel)
Cebulski J, Pasek D, Sozańska M, Popczyk M, Gabor J, Swinarew A.   +5 more
europepmc   +1 more source

Comparison of isothermal and cyclic oxidation behavior of twenty-five commercial sheet alloys at 1150 C [PDF]

The cyclic and isothermal oxidation resistance of 25 high-temperature Ni-, Co-, and Fe-base sheet alloys after 100 hours in air at 1150 C was compared.
Barrett, C. A., Lowell, C. E.
core   +1 more source