Results 91 to 100 of about 556,517 (293)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Unsuitability of the Oxidation-Reduction Potential Measurement for the Quantification of Fecal Redox Status in Inflammatory Bowel Disease. [PDF]

Biomedicines, 2023
Geertsema S, Jansen BH, van Goor H, Dijkstra G, Faber KN, Bourgonje AR.   +5 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Molecular oxidation-reduction junctions for artificial photosynthetic overall reaction. [PDF]

Proc Natl Acad Sci U S A, 2022
Zhang L, Li RH, Li XX, Liu J, Guan W, Dong LZ, Li SL, Lan YQ.   +7 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Fundamental Studies on Electrode Reactions Involving Oxygen, Carbon, and Hydrogen for Energy and Environmental Technologies

Electrochemistry
In biological metabolism, the conversion of materials and energy involving hydrogen, carbon, and oxygen occurs efficiently under ambient temperature and pressure conditions.
Shuji NAKANISHI
doaj   +1 more source

Reassessing the interpretation of oxidation-reduction potential in male infertility. [PDF]

Reprod Fertil, 2022
Joao F, Duval C, Bélanger MC, Lamoureux J, Xiao CW, Ates S, Benkhalifa M, Miron P.   +7 more
europepmc   +1 more source

Active Nitric Oxide Produced in the Red Cell under Hypoxic Conditions by Deoxyhemoglobin-mediated Nitrite Reduction [PDF]

, 2003
Enika Nagababu, Somasundaram Ramasamy, Nicholas M. P. King, Joseph M. Rifkind   +3 more
openalex   +1 more source

Mechanism of Reduction of Drought-Induced Oxidative Stress in Maize Plants by Fertilizer Seed Coating [PDF]

, 2022
Natalia Matłok, Tomasz Piechowiak, Kamil Królikowski, Maciej Balawejder   +3 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source