Results 91 to 100 of about 391,773 (316)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Oxidation-Resistant Amorphous Zinc Tin Nitride Films with Tunable Optical and Electrical Properties
, 2022 Zinc tin nitride (ZTN) compounds exhibit excellent optical and defect-tolerance properties desirable for optoelectronic applications. However, the synthesis of high-phase-purity ZTN is limited by oxidation.
Joonyun Kim (8822198) +9 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Effect of diffusion on coating microstructure and oxidation resistance of aluminizing steel
, 2001 The effect of diffuse treatment on coating microstructure and oxidation resistance at high-temperature of hot-dip aluminum were studied by means of TEM, SEM and XRD.
Li TF, 夏原, 姚枚, 于升学
core
, 2017 The boron nitride (BN) monolayer (1L) with high impermeability and resistivity seems to hold promise as a long-term corrosion barrier for Cu under ambient condition, which is supported by recent researches.
Ren, Siming +9 more
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Oxidation-Mediated, Zwitterionic Polydopamine Coatings for Marine Antifouling Applications
, 2018 We synthesized a zwitterionic dopamine derivative (ZW-DOPA) containing both catechol and amine groups, and we demonstrated an excellent marine antifouling surface by controlling the oxidation of ZW-DOPA. The oxidation was mediated by the deprotonation of
Woo Kyung Cho (2515354) +11 more
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Investigation on the High-Temperature Oxidation Resistance of Ni-(3~10) Ta and Ni-(3~10) Y Alloys
Metals, 2019 Ni-(3~10) Ta and Ni-(3~10) Y alloys were fabricated by vacuum arc melting. The oxidation resistance of the alloys was studied by cyclic and isothermal oxidation tests at 800 °C in static air.
Hang Duan +4 more
doaj +1 more source