Results 221 to 230 of about 1,805,183 (344)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Perioperative Oxidative Stress and Sepsis: Pathophysiological and Clinical Implications. [PDF]

Cureus
Dragoescu AN, Padureanu V, Stanculescu AD, Andrei M, Radu M, Padureanu R, Iliescu DG, Dragoescu PO.   +7 more
europepmc   +1 more source

Regulation of Hsp27 Oligomerization, Chaperone Function, and Protective Activity against Oxidative Stress/Tumor Necrosis Factor α by Phosphorylation [PDF]

, 1999
Thorsten Rogalla, Monika Ehrnsperger, Xavier Préville, Alexey Kotlyarov, Gudrun Lutsch, Cécile Ducasse, Catherine Paul, Martin Wieske, André‐Patrick Arrigo, Johannes Büchner, Matthias Gaestel   +10 more
openalex   +1 more source

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage Polarization

Advanced Biology, EarlyView.
This study explores the use of collagen‐hyaluronic acid (HA) hydrogels for the 3D culture of macrophages, providing a useful tool for modelling macrophage behavior in tissues and diseases. It highlights how hydrogel composition, mechanical properties, and preparation methods influence macrophage behavior, revealing for the first time that HA's ...
Tiah CL Oates, Jasmin Boyd, Louise Dolan, C de Kergariou, Jingwen Zhu, Ash Toye, Adam W Perriman, Asme Boussahel   +7 more
wiley   +1 more source

Perspectives on Alzheimer's Disease Treatment Based on Counteracting Oxidative Stress. [PDF]

Biomolecules
Bilski R, Dąbkowski S, Kozieł I, Kozicki M, Małachowska A, Przygocki M, Tyska O.   +6 more
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Nutraceuticals Against Oxidative Stress in Allergic Diseases. [PDF]

Biomolecules
Di Salvo M, Ventre A, Dato E, Casciaro M, Gangemi S.   +4 more
europepmc   +1 more source

Exercise-induced oxidative stress

, 1993
Helaine M. Alessio
openalex   +1 more source

Oxidative stress and role of antioxidants in normal and abnormal sperm function [PDF]

, 1996
Suresh C. Sikka
openalex   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source