Results 51 to 60 of about 192,135 (306)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Phase composition and transformations in magnetron-sputtered (Al,V)2O3 coatings

, 2019
Coatings of (Al1-xVx)2O3, with x ranging from 0 to 1, were deposited by pulsed DC reactive sputter deposition on Si(100) at a temperature of 550 {\deg}C. XRD showed three different crystal structures depending on V-metal fraction in the coating: {\alpha}-
Ahlgren, M., Alling, B., Carlström, C-F., Eklund, P., Göthelid, E., Hultman, L., Jõesaar, M. J., Landälv, L., Lu, J., Primetzhofer, Daniel   +9 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Impact of Pt/Al ratios on the cyclic oxidation and TCP precipitation of β-(Ni, Pt)Al coated superalloy at 1150 °C

Journal of Materials Research and Technology
The cyclic oxidation and topologically close-packed (TCP) phase precipitation behaviors of β-(Ni, Pt)Al coatings with different Pt/Al ratios at 1150 °C were investigated.
Haiyong Zou, Bin Yin, Tongyun Hu, Peng Deng, Jie Mao, Jie Cai, Yinqun Hua, Xiaofeng Zhang   +7 more
doaj   +1 more source

Production of oxide coatings by sol-gel method and electrophoresis

Current Issues in Pharmacy and Medical Sciences, 2017
The paper reports the results of depositing SiO2 and SiO2-TiO2 coatings on titanium alloy Ti-6Al-4V ELI (ASTM-grade 5). Oxide coatings were deposited onto the titanium alloy substrate by sol-gel method and by electrophoresis.
Walczak Mariusz, Drozd Kazimierz
doaj   +1 more source

The effect of (Ti + Al): V ratio on the structure and oxidation behaviour of TiAlN/VN nano-scale multilayer coatings [PDF]

, 2003
Nano-scaled multilayered TiAlN/VN coatings have been grown on stainless steel and M2 high speed steel substrates at U-B = - 85 V in an industrial, four target, Hauzer HTC 1000 coater using combined cathodic steered arc etching/unbalanced magnetron ...
Creasey, S. J., Ehiasarian, A. P., Forsyth, J. J., Hovsepian, P. E., Lewis, D. B., Luo, Q., Munz, W. D., Rainforth, W. M., Zhou, Z.   +8 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Method of forming oxide coatings [PDF]

, 1983
This invention is concerned with an improved plating process for covering a substrate with a black metal oxide film. The invention is particularly directed to making a heating panel for a solar collector.
Mcdonald, G. E.
core   +1 more source

Measurements of a low temperature mechanical dissipation peak in a single layer of Ta2O5 doped with TiO2 [PDF]

, 2008
Thermal noise arising from mechanical dissipation in oxide coatings is a major limitation to many precision measurement systems, including optical frequency standards, high resolution optical spectroscopy and interferometric gravity wave detectors ...
A Gretarsson, A Remillieux, A Zimmer, Acernese F, Anderson O L, Braginsky V B, C Comtet, C Michel, C Schwarz, Crooks D, Crooks D R M, Crooks D R M, G Harry, H Armandula, Harry G, Harry G M, I MacLaren, I Martin, J Hough, J-L Montorio, J-M M Mackowski, Lunin B S, Lück H, M M Fejer, Martin P Townsend P Weihs T Sanchez J Borgesen P, N Morgado, Nowick A, P Seidel, Penn S D, R Nawrodt, R Route, Rowan S, S Penn, S Reid, S Rowan, Schmidt-Kaler F, Takahashi R, Uchiyama T, W Vodel, Yasamura K Y   +39 more
core   +4 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source