Results 11 to 20 of about 165,130 (300)

Biochemical properties, tissue expression, and gene structure of a short chain dehydrogenase/reductase able to catalyze cis-retinol oxidation

open access: yesJournal of Lipid Research, 1999
We have identified a retinol dehydrogenase (cRDH) that catalyzes the oxidation of 9-cis- but not all-trans-retinol and proposed that this enzyme plays an important role in synthesis of the transcriptionally active retinoid, 9-cis-retinoic acid.
Mary V. Gamble   +5 more
doaj   +1 more source

Local frustration determines loop opening during the catalytic cycle of an oxidoreductase

open access: yeseLife, 2020
Local structural frustration, the existence of mutually exclusive competing interactions, may explain why some proteins are dynamic while others are rigid. Frustration is thought to underpin biomolecular recognition and the flexibility of protein-binding
Lukas S Stelzl   +7 more
doaj   +1 more source

Deciphering the Role of Selenoprotein M

open access: yesAntioxidants, 2023
Selenocysteine (Sec), the 21st amino acid, is structurally similar to cysteine but with a sulfur to selenium replacement. This single change retains many of the chemical properties of cysteine but often with enhanced catalytic and redox activity ...
Lance G. A. Nunes   +4 more
doaj   +1 more source

Electron Transport Chain Is Biochemically Linked to Pilus Assembly Required for Polymicrobial Interactions and Biofilm Formation in the Gram-Positive Actinobacterium Actinomyces oris. [PDF]

open access: yes, 2017
The Gram-positive actinobacteria Actinomyces spp. are key colonizers in the development of oral biofilms due to the inherent ability of Actinomyces to adhere to receptor polysaccharides on the surface of oral streptococci and host cells.
Belkys C. Sanchez   +5 more
core   +2 more sources

Chloride intracellular channel 3: a secreted pro-invasive oxidoreductase [PDF]

open access: yes, 2017
No abstract ...
Norman, Jim, Zanivan, Sara
core   +1 more source

Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]

open access: yes, 2016
The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R.   +2 more
core   +4 more sources

Electrochemical Investigation of the Influence of K2[B3O3F4OH] on the Activity of Immobilized Superoxide Dismutase

open access: yesInternational Journal of Electrochemical Science, 2018
It is known that oxidoreductase is responsible for the regulation of oxidative stress in organisms, and pathological changes occur within the cell in the form of accumulation or lack of superoxide and peroxide radicals if the oxidoreductase activity is ...
Safija Herenda   +5 more
doaj   +1 more source

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone [PDF]

open access: yes, 2020
Alterations in the NRF2/KEAP1 pathway result in the constitutive activation of NRF2, leading to the aberrant induction of antioxidant and detoxification enzymes, including NQO1.
Boothman, David A.   +6 more
core   +1 more source

The Spermatophore in Glossina morsitans morsitans: Insights into Male Contributions to Reproduction. [PDF]

open access: yes, 2016
Male Seminal Fluid Proteins (SFPs) transferred during copulation modulate female reproductive physiology and behavior, impacting sperm storage/use, ovulation, oviposition, and remating receptivity.
Abd-Alla, Adly MM   +8 more
core   +2 more sources

Repurposing drugs to target nonalcoholic steatohepatitis [PDF]

open access: yes, 2019
Nonalcoholic fatty liver disease (NAFLD) is a complex disorder that has evolved in recent years as the leading global cause of chronic liver damage.
Pirola, Carlos José   +1 more
core   +1 more source

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