Results 11 to 20 of about 165,130 (300)
We have identified a retinol dehydrogenase (cRDH) that catalyzes the oxidation of 9-cis- but not all-trans-retinol and proposed that this enzyme plays an important role in synthesis of the transcriptionally active retinoid, 9-cis-retinoic acid.
Mary V. Gamble +5 more
doaj +1 more source
Local frustration determines loop opening during the catalytic cycle of an oxidoreductase
Local structural frustration, the existence of mutually exclusive competing interactions, may explain why some proteins are dynamic while others are rigid. Frustration is thought to underpin biomolecular recognition and the flexibility of protein-binding
Lukas S Stelzl +7 more
doaj +1 more source
Deciphering the Role of Selenoprotein M
Selenocysteine (Sec), the 21st amino acid, is structurally similar to cysteine but with a sulfur to selenium replacement. This single change retains many of the chemical properties of cysteine but often with enhanced catalytic and redox activity ...
Lance G. A. Nunes +4 more
doaj +1 more source
Electron Transport Chain Is Biochemically Linked to Pilus Assembly Required for Polymicrobial Interactions and Biofilm Formation in the Gram-Positive Actinobacterium Actinomyces oris. [PDF]
The Gram-positive actinobacteria Actinomyces spp. are key colonizers in the development of oral biofilms due to the inherent ability of Actinomyces to adhere to receptor polysaccharides on the surface of oral streptococci and host cells.
Belkys C. Sanchez +5 more
core +2 more sources
Chloride intracellular channel 3: a secreted pro-invasive oxidoreductase [PDF]
No abstract ...
Norman, Jim, Zanivan, Sara
core +1 more source
Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]
The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R. +2 more
core +4 more sources
It is known that oxidoreductase is responsible for the regulation of oxidative stress in organisms, and pathological changes occur within the cell in the form of accumulation or lack of superoxide and peroxide radicals if the oxidoreductase activity is ...
Safija Herenda +5 more
doaj +1 more source
Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone [PDF]
Alterations in the NRF2/KEAP1 pathway result in the constitutive activation of NRF2, leading to the aberrant induction of antioxidant and detoxification enzymes, including NQO1.
Boothman, David A. +6 more
core +1 more source
The Spermatophore in Glossina morsitans morsitans: Insights into Male Contributions to Reproduction. [PDF]
Male Seminal Fluid Proteins (SFPs) transferred during copulation modulate female reproductive physiology and behavior, impacting sperm storage/use, ovulation, oviposition, and remating receptivity.
Abd-Alla, Adly MM +8 more
core +2 more sources
Repurposing drugs to target nonalcoholic steatohepatitis [PDF]
Nonalcoholic fatty liver disease (NAFLD) is a complex disorder that has evolved in recent years as the leading global cause of chronic liver damage.
Pirola, Carlos José +1 more
core +1 more source

