Results 21 to 30 of about 1,328 (132)

Oxidoreductases that act as conditional virulence suppressors in Salmonella enterica serovar Typhimurium.

, 2013
In Salmonella enterica serovar Typhimurium, oxidoreductases of the thioredoxin superfamily contribute to bacterial invasiveness, intracellular replication and to the virulence in BALB/c mice as well as in the soil nematode Caenorhabditis elegans.
Xiao Hui Sem, Anwar, N,, Mikael Rhen, Rhen, M,, Naeem Anwar, Naeem Anwar (418076), Xiao Hui Sem (418077), Sem, XH, Mikael Rhen (132322)   +8 more
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Mitochondrial Quality Control in Health and Disease

MedComm, Volume 6, Issue 8, August 2025.
Mitochondrial quality control (MQC) maintains cellular homeostasis by coordinating various processes such as fission, fusion, mitophagy, and mitochondria‐regulated cell death. Dysregulation of these mechanisms plays a key role in the development of many human diseases.
Lin Ye, Xinzhi Fu, Qi Li
wiley   +1 more source

Characteristic, Regulation and Targeting Strategies of Cancer Stem Cells and Their Niche in Digestive System Tumors

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Cancer stem cells, characterized by self‐renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription factors, metabolism and noncoding RNAs, as well as environmental cells (including tumor cells, immune cells and stromal cells), environmental factors and distant ...
Zhenzhen Chen, Huanle Qi, Yapeng Xue, Yaqi Zhang, Zhuo Zhang, Shun Xu, Shixin Liao, Xiaoyu Zeng, Jiayi Wu, Xinrui Lv, Qiankun He, Pingping Zhu   +11 more
wiley   +1 more source

Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities

Cancer Communications, Volume 45, Issue 5, Page 577-607, May 2025.
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan, Jinling Song, Yuqing Ren, Yuyuan Zhang, Yuhao Ba, Peng Luo, Quan Cheng, Hui Xu, Siyuan Weng, Anning Zuo, Shutong Liu, Xinwei Han, Jinhai Deng, Zaoqu Liu   +13 more
wiley   +1 more source

Structural determination of archaeal UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with the bacterial cell wall intermediate UDP-N-acetylmuramic acid

, 2022
The crystal structure of UDP-N-acetylglucosamine 4-epimerase (UDP-GlcNAc 4-epimerase; WbpP; EC 5.1.3.7), from the archaeal methanogen Methanobrevibacter ruminantium strain M1, was determined to a resolution of 1.65 Å. The structure, with a single monomer
Linley Schofield (15394772), Andrew Sutherland-Smith (15394775), Ron Ronimus (5484935), Vince Carbone (15395420), Carrie Sang (254175)   +4 more
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Pilot Scale Production of a F420 Precursor Under Microaerobic Conditions

Biotechnology Journal, Volume 20, Issue 3, March 2025.
Graphical Abstract and Lay Summary This work studies the influence of oxygen availability on heterologous biosynthesis of the redox co‐factor FO with an engineered E. coli strain up to pilot scale. Microaerobic conditions led to a counter selection of the unwanted natural side product riboflavin and substantially increased titers of FO.
Annika Lenić, Bettina Bardl, Florian Kloss, Gundela Peschel, Ivan Schlembach, Gerald Lackner, Lars Regestein, Miriam A. Rosenbaum   +7 more
wiley   +1 more source

Structural insights and biological activities of flavonoids: Implications for novel applications

Food Frontiers, Volume 6, Issue 1, Page 218-247, January 2025.
It provides a theoretical basis for the development of new applications of flavonoids and facilitates the targeted functional molecular design and development in the food and pharmaceutical industries. In this paper, the structural characteristics of flavonoids were summarized, and the biosynthesis, digestion and absorption of flavonoids in vivo were ...
Sheng Tang, Botao Wang, Xin Liu, Wenxia Xi, Yuanyuan Yue, Xiang Tan, Junying Bai, Linhua Huang   +7 more
wiley   +1 more source

Nitric oxide activation and reduction by heme-copper oxidoreductases and nitric oxide reductase

, 2008
The understanding of the dynamics and conformational control involved in the interplay between structure and function of nitric oxide reductase (Nor) and heme-copper oxidoreductases in their function to convert nitric oxide (NO) to nitrous oxide (N2O) is
Varotsis, Constantinos, Pinakoulaki, Eftychia   +1 more
core   +1 more source

Unveiling the potentials and action mechanisms of Citri reticulatae Pericarpium as an anti‐inflammatory food

Food Frontiers, Volume 6, Issue 1, Page 163-184, January 2025.
The review summarized advances in utilizing CRP for the prevention and treatment of inflammation under various pathological conditions. The underlying mechanism has focused on polymethoxyflavones (PMFs) present in CRP and its interaction with gut microbiota. Abstract Modern lifestyle has led human body under a frequent exposure of chronic inflammation.
Yanyi Li, Ying Chen, Yue Zhou, Jiayi He, Qian Zhou, Mingfu Wang   +5 more
wiley   +1 more source

Microbial preparation of intracellular oxidoreductases for food purposes

, 2015
Development and optimization of pilot cultivations and DSP of induced intracellular oxidoreductases microbial productions.\n\
Prell, Aleš
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