Results 31 to 40 of about 6,948 (126)
Microbiology, 2005 In Gram-negative bacterial cells, disulfide bond formation occurs in the oxidative environment of the periplasm and is catalysed by Dsb (disulfide bond) proteins found in the periplasm and in the inner membrane. In this report the identification of a new
Anna Raczko +5 more
semanticscholar +1 more source
Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Cancer Communications, Volume 45, Issue 5, Page 577-607, May 2025.Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan +13 more
wiley +1 more source
Journal of the American Chemical Society, 2006 Selenoenzymes have a central role in maintaining cellular redox potential. These enzymes have selenenylsulfide bonds in their active sites that catalyze the reduction of peroxides, sulfoxides, and disulfides.
N. Metanis, E. Keinan, P. Dawson
semanticscholar +1 more source
Pilot Scale Production of a F420 Precursor Under Microaerobic Conditions
Biotechnology Journal, Volume 20, Issue 3, March 2025.Graphical Abstract and Lay Summary This work studies the influence of oxygen availability on heterologous biosynthesis of the redox co‐factor FO with an engineered E. coli strain up to pilot scale. Microaerobic conditions led to a counter selection of the unwanted natural side product riboflavin and substantially increased titers of FO.
Annika Lenić +7 more
wiley +1 more source
Cell Death and Disease, 2013 Evasion of apoptosis, for example, by inhibitor of apoptosis (IAP) proteins, contributes to treatment resistance and poor outcome in acute myeloid leukemia (AML).
L. Steinhart, Katharina Belz, S. Fulda
semanticscholar +1 more source
Structural insights and biological activities of flavonoids: Implications for novel applications
Food Frontiers, Volume 6, Issue 1, Page 218-247, January 2025.It provides a theoretical basis for the development of new applications of flavonoids and facilitates the targeted functional molecular design and development in the food and pharmaceutical industries. In this paper, the structural characteristics of flavonoids were summarized, and the biosynthesis, digestion and absorption of flavonoids in vivo were ...
Sheng Tang +7 more
wiley +1 more source
Food Frontiers, Volume 6, Issue 1, Page 163-184, January 2025.The review summarized advances in utilizing CRP for the prevention and treatment of inflammation under various pathological conditions. The underlying mechanism has focused on polymethoxyflavones (PMFs) present in CRP and its interaction with gut microbiota. Abstract Modern lifestyle has led human body under a frequent exposure of chronic inflammation.
Yanyi Li +5 more
wiley +1 more source
Protein posttranslational modifications in metabolic diseases: basic concepts and targeted therapies
MedComm, Volume 5, Issue 10, October 2024.Posttranslational modifications of proteins are involved in the development of metabolism‐related diseases such as diabetes mellitus, obesity, hyperlipidemia, and nonalcoholic fatty liver disease. PTMs mediates the development of diabetes mellitus by affecting insulin homeostasis, glucose metabolism, diabetic complications, gluconeogenesis, and β‐cell ...
Yunuo Yang +4 more
wiley +1 more source
Genome-wide association and transcriptome analysis reveals serum ghrelin to be linked with GFRAL [PDF]
arXiv, 2020 Objective: Ghrelin is an orexigenic peptide hormone involved in the regulation of energy homeostasis, food intake and glucose metabolism. Serum levels increase anticipating a meal and fall afterwards. Underlying genetic mechanisms of the ghrelin secretion are unknown.
arxiv