This paper reviews the state of the art and recent developments in thin‐film biosensors for the detection of neurotransmitters, small molecules, and biomarkers within flexible, implantable bioelectronic systems. It covers the main sensing modalities, including electrochemical, plasmonic, acoustic, and magnetic, alongside their materials, transduction ...
Massimo Mariello
wiley +1 more source
Discovery of industrially relevant oxidoreductases [PDF]
Oxidoreductases are a family of enzymes that have a role in various reduction, oxidation, and oxyfunctionalization reactions. They cleave chemical bonds to facilitate electron transfer from a reduced organic substrate (donor) to another chemical compound
Rajan, Kezia
core
Insights from a Multi-Omics Integration (MOI) study in Oil Palm (Elaeis guineensis Jacq.) response to abiotic stresses: Part Two-Drought. [PDF]
Drought and salinity are two of the most severe abiotic stresses affecting agriculture worldwide and bear some similarities regarding the responses of plants to them.
ABDELNUR, P. V. +9 more
core
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou +9 more
wiley +1 more source
This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu +4 more
wiley +1 more source
The Role of RANBP3L in Pan‐Cancer With Its Significance in Hepatocellular Carcinoma
ABSTRACT Background RAN binding protein 3‐like (RANBP3L), a member of the Ran‐binding protein family, has been linked to various cellular functions, but the role in cancer remains underexplored. In this research, we assessed the diagnostic and prognostic value of RANBP3L in pan‐cancer, especially in liver hepatocellular carcinoma (LIHC).
Beini Cen, Jie Li, Chao Wang
wiley +1 more source
Transcriptome and proteome dynamics in chemostat culture reveal how Campylobacter jejuni modulates metabolism, stress responses and virulence factors upon changes in oxygen availability [PDF]
Campylobacter jejuni, the most frequent cause of food-borne bacterial gastroenteritis worldwide, is a microaerophile that has to survive high environmental oxygen tensions, adapt to oxygen limitation in the intestine and resist host oxidative attack ...
Al-Haideri +66 more
core +1 more source
Exploring and Validating the Molecular Mechanisms Linking Fatty Acid Metabolism and Sarcopenia
This study provides reference for fatty acid metabolism related potential candidate genes for sarcopenia and initially creates an effective machine learning models for further investigating the direction of the mechanism level. ABSTRACT Sarcopenia is an ageing‐related disease characterised primarily by skeletal muscle functional decline.
Ruopeng Yang, Shan Gu, Yang Li, Ping Xia
wiley +1 more source
PRODUCTION AND OPTIMIZATION OF CHOLESTEROL OXIDASE FROM RHODOCOCCUS SPECIES [PDF]
Objective: Optimization of conditions for cholesterol oxidase production by the microorganism isolated from urban compost and dairy soil samples.Methods: Isolates were obtained on the basis of their capability of growing on isolation medium A and B and ...
Kaur, Harjot Pal +3 more
core
Functional Coverage of the Human Genome by Existing Structures, Structural Genomics Targets, and Homology Models [PDF]
The bias in protein structure and function space resulting from experimental limitations and targeting of particular functional classes of proteins by structural biologists has long been recognized, but never continuously quantified.
Janet Thornton, Lei Xie, Philip E Bourne
core +5 more sources

