Results 81 to 90 of about 54,380 (260)

Nebulization of Mesenchymal Stem Cells Secretome Attenuates Acute Respiratory Distress Syndrome Caused by SARS-CoV-2 Corona Virus: An Open-Label, Controlled Trial

Advanced Biomedical Research
Background: Previous investigations have indicated the potential of mesenchymal stem cell (MSC) transplantation in treating COVID-19. However, the limited lifespan of transplanted cells constrains this therapeutic approach.
Masoumeh Baghalishahi, Maysam Yousefi, Seyed Noureddin Nematollahi-Mahani, Mahsa Ziasistani, Fahimeh Pourjafari, Mona Saheli   +5 more
doaj   +1 more source

From variant detection to interpretation in idiopathic erythrocytosis: A structured approach applied to a clinical cohort

British Journal of Haematology, EarlyView.
Targeted next‐generation sequencing combined with a structured interpretative framework integrating gene–disease validity, population data, computational predictions, ACMG criteria and structural modelling enabled prioritisation of rare variants in idiopathic erythrocytosis, highlighting the genetic heterogeneity and biological complexity underlying ...
Alessandra Giannella, Fabrizio Vianello, Simone Zoletto, Arianna Magrini, Ilaria Gianesello, Gianni Binotto, Nicolo’ Danesin, Jessica Ceccato, Giulia Gualtiero, Maria Piazza, Samuela Carraro, Valeria Carabotta, Francesco Cinetto, Alessandro Cellini, Marco Carraro, Carmela Gurrieri, Laura Pavan, Francesco Piazza, Andrea Visentin, Walter Ageno, Livio Trentin, Giulio Ceolotto   +21 more
wiley   +1 more source

Methaemoglobinaemia: From pathophysiology to contemporary clinical management

British Journal of Haematology, EarlyView.
Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley   +1 more source

Predict less, prevent more: A familiar mantra for sickle cell anaemia?

British Journal of Haematology, EarlyView.
Commentary on: Sommet J, Boizeau P, Haouari Z, et al. Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia. Br J Haematol. 2026 (Online ahead of print). doi: 10.1111/bjh.70726.
Charles T. Quinn
wiley   +1 more source

The Start of a Good Innings, 50 Years of Intensive Care Medicine

World Journal of Surgery, EarlyView.
Jonathan Oliver White, Timothy Craig Hardcastle, David Zonies, Simon Robertson, Sérgio Faria Baptista   +4 more
wiley   +1 more source

Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia

British Journal of Haematology, EarlyView.
Summary Cerebral macrovasculopathy (CV) is a major complication in children with sickle cell anaemia (SCA) and usually requires a long‐term transfusion programme (TP) to prevent stroke. This study aimed to identify factors predicting reversal of CV on TP in a single‐centre newborn cohort. Among 375 patients, 50 presented CV and received TP.
Julie Sommet, Priscilla Boizeau, Zinedine Haouari, Berengère Koehl, Monique Elmaleh, Emmanuelle Lesprit, Florence Missud, Ghislaine Ithier, Laurent Holvoet, Valentine Brousse, Christophe Delclaux, André Denjean, Suzanne Verlhac, Corinne Alberti, André Baruchel, Nathalie Couque, Malika Benkerrou   +16 more
wiley   +1 more source

Nocturnal Hypoxemia Burden Correlates With Vestibular Dysfunction in Obstructive Sleep Apnea

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction Obstructive sleep apnea (OSA) is a potential contributor to vestibular dysfunction, though specific correlating parameters remain unclear. This study aimed to determine whether hypoxemia severity indices correlate quantitatively with caloric slow‐phase eye velocity (SPV), a marker of vestibular function. Methods In a retrospective
Dachan Kim, Seong Hoon Bae, Hyung‐Ju Cho   +2 more
wiley   +1 more source

Implementation, Validation and Clinical Testing of Oximetry Device for Microcirculation Assessment in Oral Tissue

Sensors
The recent rise in living standards has been accompanied by increased awareness and emphasis on oral health. Non-invasive assessment of gingival microcirculation and accurate evaluation of oxygen supply to oral tissues are critical for the early ...
Hojat Lotfi, Bibiana Falcão, Valentina Vassilenko   +2 more
doaj   +1 more source

Acute and sudden death secondary to cardiac tamponade during anaesthetic recovery in a 21‐year‐old draught mule

Equine Veterinary Education, EarlyView.
Summary This case report is of educational value and contributes to the literature because it describes a unique death after anaesthesia due to cardiac tamponade from a rare cardiac neoplasm. In trying to diagnose the origin of chronic sinusitis, a geriatric mule mare was anaesthetised and during recovery, died acutely.
A. Carroll, J. Quandt, S. Dantino
wiley   +1 more source

Peripheral perfusion-guided versus routine fluid therapy in sepsis: A randomized controlled pilot trial

Journal of Research in Medical Sciences
Background: Sepsis remains a leading cause of morbidity and mortality among critically ill patients. Fluid resuscitation is essential, but conventional protocols often lack individualized assessment of tissue perfusion, risking underresuscitation or ...
Nima Vaziri, Babak Alikiaii, Shadi Farsaei, Sarah Mousavi   +3 more
doaj   +1 more source