Results 121 to 130 of about 5,363,213 (311)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Salinity and stable oxygen isotope relationship in the Southwestern Atlantic: constraints to paleoclimate reconstructions

Anais da Academia Brasileira de Ciências
: Stable isotopes have been widely used in the literature both to discuss current ocean circulation processes, as well as to reconstitute paleoceanographic parameters. The distribution of oxygen and deuterium stable isotopes in seawater (δ18Osw and δDsw)
ANDRE L. BELEM, CAMILLA CARICCHIO, ANA LUIZA S. ALBUQUERQUE, IGOR M. VENANCIO, MARIA DO R. ZUCCHI, TARCIO HENRIQUE R. DOS SANTOS, YACI GALLO ALVAREZ   +6 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Proteomic Data and Drug Implications for Cerebral Microvascular Endothelial Cells Under Varying Oxygen Levels

Scientific Data
Hyperoxia in standard cell cultures (18 kPa O2) imposes cellular oxidative stress, potentially skewing research and drug screening outcomes. Cerebral microvascular endothelial cells (hCMEC/D3) experience no more than 7 kPa O2 in vivo.
Sarah Barakat, Fan Yang, Hayriye Ecem Yelkenci, Kıvanç Kök, Giovanni E. Mann, Emrah Eroğlu   +5 more
doaj   +1 more source

Highly Efficient Solar Steam Generation by W₁₈O₄₉@PVA Gels

Gels
Oxygen-deficient tungsten oxide W18O49 was synthesized through lattice oxygen escaping at high temperature in N2 atmosphere. The temperature and inert atmosphere were critical conditions to initiate the lattice oxygen escaping to obtain W18O49. The large
Jiefeng Yan, Zhenxing Fang, Jinxing Hu, Yangming Sun, Xinyi Huang, Guannan Zhou, Lu Li, Rui Wang, Yan Chen   +8 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Cosmogenic Isotopes Unravel the Hydrochronology and Water Storage Dynamics of the Southern Sierra Critical Zone

Water Resources Research, 2019
One of the principal questions in hydrology is how and when water leaves the critical zone storage as either stream flow or evapotranspiration.
A. Visser, M. Thaw, A. Deinhart, R. Bibby, M. Safeeq, M. Conklin, B. Esser, Y. Van der Velde   +7 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Using oxygen 18 isotope to problematize the presence of resettled laborers in the far provinces of the Inca empire. [PDF]

PLoS One, 2020
Garrido F, Morales C.
europepmc   +1 more source