Results 101 to 110 of about 6,998,665 (296)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

The self-referencing oxygen-selective microelectrode: Detection of transmembrane oxygen flux from single cells

open access: yes, 1999
A self-referencing, polarographic, oxygen-selective microelectrode was developed for measuring oxygen fluxes from single cells. This technique is based on the translational movement of the microelectrode at a known frequency through an oxygen gradient ...
Porterfield, D.M.   +3 more
core   +1 more source

Investigating the climatic parameter of enviroment temperature using oxygen 18 isotope analysis and carbon13 in Jazmurian playa [PDF]

open access: yesتحقیقات کاربردی علوم جغرافیایی
Reconstructing paleoclimate, particularly environmental temperature, plays a crucial role in understanding both current and future climate patterns. The aim of this research is to investigate the climatic conditions and estimate the ambient temperature ...
arefe shabani eraghi   +2 more
doaj  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Efficacy of a novel oxygen scavenger mask in reducing local oxygen concentrations below the surgical fire risk threshold: an experimental proof-of-concept study

open access: yesPatient Safety in Surgery
Background This study aims to evaluate the efficacy of an oxygen scavenging mask device in reducing local oxygen concentrations from nasal cannula ventilation compared to a standard open facial surgical field.
Christopher D. Yang   +2 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Oxygen Isotope Fractionation in the Martian Atmosphere Induced by CO2 Photolysis and O3 Formation

open access: yesThe Planetary Science Journal
The enrichment of heavy isotopes of volatile elements in the Martian atmosphere indicates that Mars lost a large portion of its atmosphere through escape to space. Recent atmospheric measurements by the ExoMars Trace Gas Orbiter (TGO) have suggested that
Tatsuya Yoshida   +10 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Part of the global seawater delta oxygen-18 database from reference Schriber 1974

open access: yes, 2001
Part of the global seawater delta oxygen-18 database from reference Schriber ...
G Schriber (7892828), Schriber, G
core   +1 more source

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