Results 81 to 90 of about 6,998,665 (296)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Current Indiana Oxygen Headquarters, Indianapolis
, 1990 As Indiana Oxygen grew, it began to open satellite branch stores, the first in Muncie in 1978. The increased demand for gas products required Indiana Oxygen to move again in 1991 to a new state-of-the-industry palletized cylinder fill plant on ...
core
Aquatic respiration rate measurements at low oxygen concentrations.
PLoS ONE, 2014 Despite its huge ecological importance, microbial oxygen respiration in pelagic waters is little studied, primarily due to methodological difficulties.
Moritz Holtappels +5 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Indiana Oxygen Company Opens, 1915
, 1910 They found a new venture in 1915 when they combined their engineering and sales talents to form Indiana Oxygen Company, the first industrial gas production plant in the state of Indiana, located on S. Harmon Street in Indianapolis.
core
Part of the global seawater delta oxygen-18 database from reference Punning 1991
, 2001 Part of the global seawater delta oxygen-18 database from reference Punning ...
Ya-M K Punning (6970652) +1 more
core +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Indiana Oxygen Expands Products to Include Specialty Gases
, 1960 In 1960, the old air separation plant was replaced by new liquid oxygen, nitrogen, argon and CO2 pumping systems. With this change, Indiana Oxygen began producing specialty gases (Spec Gas) and research laboratory-grade high purity blends.Use of this ...
core
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source