Results 71 to 80 of about 5,363,213 (311)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A seasonal precipitation isoscape for New Zealand

Journal of Hydrology: Regional Studies
Region: New Zealand Focus: Application of a seasonal precipitation isoscape for New Zealand, to incorporate influences of regional scale atmospheric circulation, and local topography.
B.D. Dudley, A.F. Hill, A. McKenzie
doaj   +1 more source

The effects of repeated propofol anesthesia on spatial memory and long-term potentiation in infant rats under hypoxic conditions

Genes and Diseases, 2020
Propofol is widely used as an intravenous drug for induction and maintenance in general anesthesia. Hypoxemia is a common complication during perianesthesia.
Mang Sun, Ruixue Yuan, Hui Liu, Jing Zhang, Shengfen Tu   +4 more
doaj   +1 more source

Wisconsin Oxygen/Hydrogen Company, Kenosha, Wisconsin 1920-1925

, 1920
It wasn’t long before the Brant Brothers expanded their entrepreneurial efforts to Kenosha, Wisconsin, where they built a second electrolytic oxygen/hydrogen plant, known as Wisconsin Oxygen/Hydrogen Company.

core  

Oxygen supply and consumption in soilless culture: evaluation of an oxygen simulation model for cucumber

, 2001
A soil oxygen simulation model (OXSI) was tested and evaluated for evaluating growing media with respect to aeration. In the model, local oxygen concentrations are calculated from coefficients of diffusion and consumption (respiration), assuming ...
Baas, R., Koolen, A.J., Stol, K.J., Wever, G., Tariku, E.   +4 more
core   +1 more source

Oxygen isotope ecology of recent planktic foraminifera at the central Walvis Ridge (SE Atlantic) [PDF]

, 2005
Above the Walvis Ridge, in the SE Atlantic Ocean, we collected living plantkic foraminifera from the upper water column using depth stratified plantkon tows. The oxygen isotope composition (
Kroon, Dirk, Dick Kroon, Brummer, G.J.A., Neven Lončarić, Brummer, G. J. A., Kroon, D., Peeters, F. J. C., Peeters, F.J.C., Geert‐Jan A. Brummer, Loncaric, N., Frank J. C. Peeters   +10 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Interpretation of groundwater origin in the Velenje coal mine on the basis of isotope composition

Geologija, 2002
The aim of the investigation was to determine the isotopic properties of cave waters from the Velenje coal mine and define the recharge areas of individual aquifers.
Janko Urbanc, Bojan Lajlar
doaj  

Hyperoxia reversibly alters oxygen consumption and metabolism [PDF]

, 2012
Aim: Ventilation with pure oxygen (hyperoxic ventilation: HV) is thought to decrease whole body oxygen consumption (VO(2)). However, the validity and impact of this phenomenon remain ambiguous; until now, under hyperoxic conditions, VO(2) has only been ...
Lauscher, Patrick, Sabine Lauscher, Habler, Oliver, Kertscho, Harry, Patrick Lauscher, Lauscher, Sabine, Oliver Habler, Jens Meier, Meier, Jens, Harry Kertscho   +9 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source