Results 71 to 80 of about 1,387,037 (263)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Employing artificial intelligence to predict δ¹⁸O and δ²H isotope ratios in precipitation in Iraq under changing climate patterns

open access: yesScientific Reports
Understanding precipitation dynamics in arid regions such as Iraq is of paramount importance in hydrological and climatological studies, as it is a key approach to water resources management and climate change adaptation.
Ali Al Maliki   +5 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Significant impact of different oxygen breathing conditions on noninvasive in vivo tumor-hypoxia imaging using [18F]-fluoro-azomycinarabino-furanoside ([18F]FAZA)

open access: yesRadiation Oncology, 2011
Background [18F]FAZA is a PET biomarker with great potential for imaging tumor hypoxia. Aim of our study was to compare [18F]FAZA uptake in mice with subcutaneous exogenous CT26 colon carcinomas and endogenous polyoma middle-T (PyV-mT) mammary carcinomas
Maier Florian C   +9 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Enrichment of oxygen-18 isotope by fractional distillation

open access: yes, 2018
Bu çalışmada, vakum altında çalışan 200 cmyüksekliğinde ve 3 cm çapında fraksiyonel su destilasyon kolonu tasarlanmış vepyrex camdan imal edilmiştir. Kolon; -0.8 bar, 52° C’de 120-140 ml/dkbuharlaşma/yoğunlaşma ve 0.5-10 ml/dk besleme hızlarında damıtılmış su(distilated water) ile çalıştırılmıştır.
GÜRBÜZ GÜNER, Selen Nimet   +4 more
openaire   +2 more sources

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Investigating the climatic parameter of enviroment temperature using oxygen 18 isotope analysis and carbon13 in Jazmurian playa [PDF]

open access: yesتحقیقات کاربردی علوم جغرافیایی
Reconstructing paleoclimate, particularly environmental temperature, plays a crucial role in understanding both current and future climate patterns. The aim of this research is to investigate the climatic conditions and estimate the ambient temperature ...
arefe shabani eraghi   +2 more
doaj  

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