Results 51 to 60 of about 1,676,233 (250)

Isolation and characterization of Alicycliphilus denitrificans strain BC, which grows on benzene with chlorate as the electron acceptor [PDF]

, 2008
A bacterium, strain BC, was isolated from a benzene-degrading chlorate-reducing enrichment culture. Strain BC degrades benzene in conjunction with chlorate reduction.
Junca, H., Tan, N.C.G., Weelink, S.A.B., Doesburg, W.C.J., van, Stams, A.J.M., Langenhoff, A.A.M., Kieboom, C., van den, Broeke, H., ten, Gerritse, J.   +8 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Oxygen-limited growth analysis.

, 2022
(a) SALARECON predictions of relative growth rate under oxygen limitation as a function of relative oxygen uptake rate. Feed composition and flux capacities were randomized 1,000 times (light blue) and the mean across conditions is shown with 95 ...
Jesse C. J. van Dam (8347527), Ove Øyås (11304636), Wout van Helvoirt (12745325), Peter J. Schaap (6680216), Jasper J. Koehorst (8347530), Simen R. Sandve (3265908), Filip Rotnes (12859584), Marie Gulla (11375150), Fabian Grammes (502784), Arne B. Gjuvsland (9096303), Jon Olav Vik (9666588), Maksim Zakhartsev (3606323), Maria Suarez-Diez (3404327), Vitor A. P. Martins dos Santos (12859590), Róbert Anton Hafþórsson (12859587), Yang Jin (78609), Liv Torunn Mydland (8201109)   +16 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The next generation of oxy-fuel boiler systems [PDF]

, 2005
Research in the area of oxy-fuel combustion which is being pioneered by Jupiter Oxygen Corporation combined with boiler research conducted by the USDOE/Albany Research Center has been applied to designing the next generation of oxy-fuel combustion ...
Patrick, Brian (Jupiter Oxygen Corp.), Summers, Cathy A., Ochs, Thomas L., Gross, Alex (Jupiter Oxygen Corp.), Turner, Paul C., Oryshchyn, Danylo B.   +5 more
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Porous fuel injection with oxygen enrichment in a viable scramjet engine [PDF]

, 2014
Oxygen enriched, porous fuel injection has been numerically investigated in this study with the aim of understanding mixing and combustion enhancements achievable in a viable scramjet engine.
Capra, Bianca R.
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source