Results 71 to 80 of about 1,676,233 (250)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Alexandria Engineering Journal, 2017 Diesel engines occupy a crucial position in automobile industry due to their high thermal efficiency and high power to weight ratio. However, they lag behind in controlling air polluting components coming out of the engine exhaust.
P. Baskar, A. Senthil Kumar
doaj +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Wisconsin Oxygen/Hydrogen Company, Kenosha, Wisconsin 1920-1925
, 1920 It wasn’t long before the Brant Brothers expanded their entrepreneurial efforts to Kenosha, Wisconsin, where they built a second electrolytic oxygen/hydrogen plant, known as Wisconsin Oxygen/Hydrogen Company.
core
Ejdrup/relative-enrichment: Relative Enrichment v0.1.0
, 2022 Original version attached to the manuscript A density-based enrichment measure for assessing colocalization in single-molecule localization microscopy data by Ejdrup et al.
Aske L Ejdrup
core +1 more source
Water Enrichment of Forming Sub-Neptune Envelopes Limited by Oxygen Exhaustion
The Astrophysical JournalThe interaction between a magma ocean and a primordial atmosphere is increasingly recognized as a key process in shaping planetary envelope compositions.
Tadahiro Kimura, Tim Lichtenberg
doaj +1 more source
Engineering Science and Technology, an International Journal, 2016 Oxygen enriched combustion is one of the attractive combustion technologies to control pollution and improve combustion in diesel engines. An experimental test was conducted on a single cylinder direct injection diesel engine to study the impact of ...
P. Baskar, A. Senthilkumar
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source