From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Age and Huddling as Determinants of Metabolic Rate in Grasshopper Mice (Onychomys leucogaster) [PDF]
The metabolic rates of grasshopper mice (Onychomys leucogaster) were determined every third day from birth to adulthood. Metabolic rates were quantitated by measuring oxygen consumption in an open circuit system.
Baeyens, Dennis A.+2 more
core +2 more sources
Effects of synchronous music on treadmill running among elite triathletes [PDF]
This is the post-print version of the final paper published in Journal of Science and Medicine in Sport. The published article is available from the link below.
Alessandra Mecozzi Saha+33 more
core +3 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan+2 more
wiley +1 more source
Relations of morphological characteristics and maximal oxygen consumption of fourth grade pupils based on gender [PDF]
On a sample of 71 respondents, 37 boys and 34 girls, age of fourth grade elementary school, accordingly 9 years +/- 6 months, it is assessed correlation and prediction of maximal oxygen consumption based measures of morphological range.
Jakovljević Vladimir+4 more
doaj +1 more source
Hypoxic training increases maximal oxygen consumption in Thoroughbred horses well-trained in normoxia. [PDF]
Hypoxic training is effective for improving athletic performance in humans. It increases maximal oxygen consumption (V̇O2max) more than normoxic training in untrained horses. However, the effects of hypoxic training on well-trained horses are unclear. We
Jones, James H+4 more
core +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source
Objective: the purpose of the study was to evaluate how high-intensity interval training affects strength, oxidative capacity and hypertrophy of working muscles in power sports athletes.
A. B. Miroshnikov+2 more
doaj +1 more source
Fluoride Increases Superoxide Production and Impairs the Respiratory Chain in ROS 17/2.8 Osteoblastic Cells [PDF]
It is known that fluoride produces oxidative stress. Inflammation in bone tissue and an impairment of the respiratory chain of liver have been described in treatments with fluoride. Whether the impairment of the respiratory chain and oxidative stress are
Fina, Brenda+3 more
core +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source