Results 61 to 70 of about 4,543,443 (401)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Processed meat consumption and lung function: modification by antioxidants and smoking [PDF]

, 2014
Unhealthy dietary patterns are associated with poorer lung function. It is not known whether this is due to low consumption of antioxidant-rich fruit and vegetables, or is a consequence of higher intakes of harmful dietary constituents such as processed ...
Okubo, H., Syddall, H.E., Aihie Sayer, A., Sayer, AA, Shaheen, S.O., Grp, HCS, Cooper, C., Ntani, G, Jameson, KA, Robinson, SM, Dennison, E.M., Dennison, EM, Cooper, Cyrus, Cooper, C, Shaheen, SO, Syddall, HE, Okubo, H, Robinson, S.M., Ntani, G.   +18 more
core   +1 more source

The effect of high-intensity interval training on hypertrophy, strength and oxidative capacity of active muscles in power sports athletes: a cross-sectional study

Спортивная медицина: наука и практика, 2020
Objective: the purpose of the study was to evaluate how high-intensity interval training affects strength, oxidative capacity and hypertrophy of working muscles in power sports athletes.
A. B. Miroshnikov, V. V. Volkov, A. V. Smolensky   +2 more
doaj   +1 more source

Relations of morphological characteristics and maximal oxygen consumption of fourth grade pupils based on gender [PDF]

Fizička Kultura, 2014
On a sample of 71 respondents, 37 boys and 34 girls, age of fourth grade elementary school, accordingly 9 years +/- 6 months, it is assessed correlation and prediction of maximal oxygen consumption based measures of morphological range.
Jakovljević Vladimir, Ljubojević Adriana, Karalić Tamara, Gerdijan Nikolina, Vukić Željko   +4 more
doaj   +1 more source

Oxygen consumption of H_11_SC

, 1994
Oxygen consumption of ...
Burke Hales (7891484), Hales, Burke, Emerson, Steven R, Archer, David E, Steven R Emerson (6963185), David E Archer (6963197)   +5 more
core   +1 more source

Chemical Basis of Reactive Oxygen Species Reactivity and Involvement in Neurodegenerative Diseases

International Journal of Molecular Sciences, 2019
Increasing numbers of individuals suffer from neurodegenerative diseases, which are characterized by progressive loss of neurons. Oxidative stress, in particular, the overproduction of Reactive Oxygen Species (ROS), play an important role in the ...
F. Collin
semanticscholar   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Effect of EMG-biofeedback robotic-assisted body weight supported treadmill training on walking ability and cardiopulmonary function on people with subacute spinal cord injuries – a randomized controlled trial

BMC Neurology, 2019
Background Body weight supported treadmill training (BWSTT) is a frequently used approach for restoring the ability to walk after spinal cord injury (SCI).
Eddy Yu Yeung Cheung, Kevin Ka Ki Yu, Rachel Lai Chu Kwan, Carmen Ka Man Ng, Rosanna Mei Wa Chau, Gladys Lai Ying Cheing   +5 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Oxygen consumption of H_9_SC

, 1994
Oxygen consumption of ...
Burke Hales (7891484), Hales, Burke, Emerson, Steven R, Archer, David E, Steven R Emerson (6963185), David E Archer (6963197)   +5 more
core   +1 more source