Results 71 to 80 of about 4,543,443 (401)

Spatial oxygen heterogeneity in a Hediste diversicolor irrigated burrow [PDF]

, 2011
The heterogeneity of oxygen distribution in a Hediste diversicolor burrow environment was investigated in a laboratory experiment using a 6-mm thick tank equipped with oxygen planar optodes. The twodimensional oxygen distribution in a complete burrow was
Franck Gilbert, Poggiale, Jean-Christophe, Cuny, Philippe, Esteves, José Luis, Philippe Cuny, José Luis Esteves, Gilbert, Franck, Laura Pischedda, Jean-Christophe Poggiale, Pischedda, Laura, Esteves, Josã© Luis, Poggiale, Jean Christophe   +11 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival [PDF]

, 2011
Hypoxia is one of the features of poorly vascularised areas of solid tumours but cancer cells can survive in these areas despite the low oxygen tension.
Tennant, D.A., Zheng, L, Appanna, VD, Watson David G., Kalna, G., Hedley Barbara A., Papkovsky, Dmitri B, Gottlieb Eyal, Papkovsky, D.B., Christian Frezza, Dmitri B. Papkovsky, Frezza, Christian, Hedley, Barbara A, Zheng Liang, Liang Zheng, Hedley, BA, Watson, DG, Kalna, Gabriela, Dmitri B Papkovsky, Tennant, Daniel A., Gabriela Kalna, Frezza, C, Watson, David, Eyal Gottlieb, Tennant Daniel A., Gottlieb, Eyal, Gottlieb, E., David G. Watson, Frezza Christian, Kalna Gabriela, Hedley, B., Daniel A Tennant, Frezza, C., Kalna, G, Barbara A. Hedley, Zheng, L., Barbara A Hedley, Tennant, Daniel; id_orcid, Gottlieb, E, David G Watson, Papkovsky, DB, Papkovsky Dmitri B., Zheng, Liang, Watson, D.G., Daniel A. Tennant   +44 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Oxygen consumption while standing iwth and unstable shoe design [PDF]

, 2014
This study explored the effects of unstable shoe design on oxygen consumption. Methods. Oxygen consumption (VO2) and heart rate (HR) were measured in 16 individuals while barefoot, wearing unstable shoes (Masai Barefoot Technology) and wearing ...
Vogt, Michael, Gasser, Benedikt, Hoppeler, Hans-Heinrich   +2 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Oxygen consumption of JGOFS_PAP6

, 2002
Oxygen consumption of ...
Richard Stephen Lampitt (7886282), Lampitt, Richard Stephen   +1 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Oxygen consumption of H_5_SC

, 1994
Oxygen consumption of ...
Burke Hales (7891484), Hales, Burke, Emerson, Steven R, Archer, David E, Steven R Emerson (6963185), David E Archer (6963197)   +5 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source