Results 121 to 130 of about 509,742 (296)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

An Analysis of the Conceptual and Functional Factors Affecting the Effectiveness of Proton-Exchange Membrane Water Electrolysis

ChemEngineering
Hydrogen has the potential to decarbonize the energy and industrial sectors in the future, mainly if it is generated by water electrolysis. The proton-exchange membrane water electrolysis (PEMWE) system is regarded as a propitious technology to produce ...
Gaydaa AlZohbi
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Glancing Angle Deposition for Enhanced Oxygen Evolution Reaction

Small Structures
The oxygen evolution reaction (OER) presents a major kinetic challenge in alkaline water electrolysis. Nickel oxide (NiO) is generally accepted as a favorable material due to its abundance and stability, yet it also exhibits limited intrinsic catalytic ...
Parsa Borhani, Aria Khalili, Ula Suliman, Jae‐Young Cho, Kenneth D. Harris, Shiva Mohajernia   +5 more
doaj   +1 more source

Electrocatalytic overall water splitting based on (ZnNiCoFeY)xOy high-entropy oxide supported on MoS2

South African Journal of Chemical Engineering
Hydrogen energy is a sustainable and clean source that can meet global energy demands without adverse environmental impacts. High-entropy oxides (HEOs), multielement (5 or more) oxides with an equiatomic or near-equatomic elemental composition, offer a ...
Sumayya C. Pathan, Jasmin S. Shaikh, Navajsharif S. Shaikh, Victor Márquez, Meena Rittiruam, Tinnakorn Saelee, Patcharaporn Khajondetchairit, Sawanta S. Mali, Jyoti V. Patil, Chang Kook Hong, Piyasan Praserthdam, Supareak Praserthdam   +11 more
doaj   +1 more source

Oxygen evolution reaction catalysis

Focus on Catalysts, 2021
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Current status of developed electrocatalysts for water splitting technologies: from experimental to industrial perspective

Nano Convergence
The conversion of electricity into hydrogen (H2) gas through electrochemical water splitting using efficient electrocatalysts has been one of the most important future technologies to create vast amounts of clean and renewable energy.
Duy Thanh Tran, Phan Khanh Linh Tran, Deepanshu Malhotra, Thanh Hai Nguyen, Tran Thien An Nguyen, Nguyen Tram Anh Duong, Nam Hoon Kim, Joong Hee Lee   +7 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source