Results 101 to 110 of about 155,256 (306)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The current state of transition metal-based electrocatalysts (oxides, alloys, POMs, and MOFs) for oxygen reduction, oxygen evolution, and hydrogen evolution reactions

open access: yesFrontiers in Energy Research
Climate change is showing its impacts now more than ever. The intense use of fossil fuels and the resulting CO2 emissions are mainly to blame, accentuating the need to develop further the available energy conversion and storage technologies, which are ...
Henrique Araújo   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A Comparative Study of Composition and Morphology Effect of NixCo1-x(OH)(2) on Oxygen Evolution/Reduction Reaction [PDF]

open access: yes, 2014
Oxygen electrochemistry has been intensely studied in the pursuit of sustainable and efficient energy conversion and storage solutions. Over the years, developing oxygen electrode catalysts with high activity and low cost remains a great challenge ...
靳健   +5 more
core  

Efficient electrocatalysts derived from praseodymium-doped MOFs and MXene for oxygen reduction, hydrogen evolution, and oxygen evolution reactions

open access: yesCarbon Trends
In response to the urgent need for high-performance non-precious metal electrocatalysts to address the energy crisis and reduce dependence on fossil fuels, we propose a novel approach to develop a highly selective and efficient electrocatalyst derived ...
Mozhgan Hadavand   +2 more
doaj   +1 more source

Application of Oxygen Reduction Reaction, Oxygen Evolution Reaction and Hydrogen Evolution Reaction in Electrochemical Biosensing

open access: yesInternational Journal of Electrochemical Science, 2022
Jianlin Zhou   +3 more
openaire   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Co doped MoS2 as Bifunctional Electrocatalyst for Hydrogen Evolution and Oxygen Reduction Reactions

open access: yesInternational Journal of Electrochemical Science, 2019
Pure MoS2 and MoS2 compounds were doped with Co using a hydrothermal method. XRD results indicate that two of the five diffraction peak results at 9.2° and 18.2° may be attributed to low crystallinity of MoS2. The (002) diffraction peaks for the Co-doped
Congrong Wang   +9 more
doaj   +1 more source

Benchmarking Heterogeneous Electrocatalysts for the Oxygen Evolution Reaction

open access: yesJournal of the American Chemical Society, 2013
Objective evaluation of the activity of electrocatalysts for water oxidation is of fundamental importance for the development of promising energy conversion technologies including integrated solar water-splitting devices, water electrolyzers, and Li-air batteries.
McCrory, Charles C. L.   +3 more
openaire   +3 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

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