Results 91 to 100 of about 155,256 (306)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

DFT Investigations on the Reaction Mechanisms in Photosynthetic Oxygen Evolution [PDF]

, 2019
Photosynthetic water oxidation and oxygen evolution are fundamental biological processes in nature, with significant and challenging scientific issues centering on the oxygen-evolving complex, as well as some conundrums and controversies in this field ...
Yu Guo, Guo, Yu,
core   +1 more source

Recent advances in alternative oxidation reactions for water splitting and their efficient electrocatalysts

工程科学学报
Developing state-of-the-art water electrolysis technologies to advance large-scale hydrogen production is an effective way to ease the current energy crisis and environmental pollution.
Miao WANG, Rongrong DENG, Qibo ZHANG
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

1D@2D Hierarchical NiCo2O4@MIL-53(Fe) Nanostructures Synergistically Enhance Oxygen Evolution Reaction [PDF]

Hierarchical nanostructures with unique synergistic electronic effects and abundant active sites play an essential role in the field of electrocatalysis.
Wu, JC, Wang, ZG, Li, X, Mao, F, Liu, PF, Ding, Z, Yang, HG   +6 more
core   +1 more source

Oxygen-Incorporated MoS₂ Nanosheets with Expanded Interlayers for Hydrogen Evolution Reaction and Pseudocapacitor Applications [PDF]

, 2016
Two-dimensional transition-metal dichalcogenides (TMDs) nanosheets have attracted tremendous research interest. Engineering the structure of MoS2 may result in desirable performance for energy applications.
Jiang Zhou (403661), Guozhao Fang (1913317), Anqiang Pan (1913326), Shuquan Liang (1913323)   +3 more
core   +1 more source

Advanced applications of pulsed laser deposition in electrocatalysts for hydrogen-electric conversion systems

Opto-Electronic Advances
Pulsed laser deposition (PLD), as an advanced synthesis technology with unparalleled control over thin films, has evolved into a universal platform for optoelectronic materials engineering. Its unique advantages including precise stoichiometric transfer,
Yuanyuan Zhou, Yong Wang, Ke Zhang, Huaqian Leng, Peter Müller-Buschbaum, Nian Li, Liang Qiao   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Electric-field-assisted proton coupling enhanced oxygen evolution reaction

Nature Communications
The discovery of Mn-Ca complex in photosystem II stimulates research of manganese-based catalysts for oxygen evolution reaction (OER). However, conventional chemical strategies face challenges in regulating the four electron-proton processes of OER ...
Xuelei Pan, Mengyu Yan, Qian Liu, Xunbiao Zhou, Xiaobin Liao, Congli Sun, Jiexin Zhu, Callum McAleese, Pierre Couture, Matthew K. Sharpe, Richard Smith, Nianhua Peng, Jonathan England, Shik Chi Edman Tsang, Yunlong Zhao, Liqiang Mai   +15 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source