Results 41 to 50 of about 385,675 (250)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Oxygen desorption – Critical step for the oxygen evolution reaction

Current Opinion in Electrochemistry, 2023
The oxygen evolution reaction (OER) has been widely investigated in computational electrocatalysis. Recent studies suggest that the final oxygen desorption step could be rate-limiting, or even inhibiting, for the classical OER mechanism on the benchmark IrO2 electrocatalyst, and a novel reaction mechanism has been proposed circumventing this bottleneck.
Binninger, Tobias, Kowalski, Piotr M., Eikerling, Michael H.   +2 more
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Oxygen vacancy-mediated high-entropy oxide electrocatalysts for efficient oxygen evolution reaction

Materials Today Catalysis
Transition metal oxides hold great potential for water splitting due to their tunable electronic structures and abundant availability. However, their inherently poor electrical conductivity and limited catalytic activity hinder their practical ...
Ruonan Liu, Yaotian Yan, Liang Dun, Taili Yang, Bin Qin, Peijia Wang, Wei Cai, Shude Liu, Xiaohang Zheng   +8 more
doaj   +1 more source

The analysis of diffusion controlled reactions with non-equal diffusivities of the reactatnts [PDF]

, 1996
We show, using as a model problem the description of the reaction of a fuel pocket with the oxygen of the environment, how to derive a system of conservation equations to describe the evolution of the temperature and concentrations of the reactants, when
Liñán Martínez, Amable
core   +1 more source

Chemistry of heavy elements in the Dark Ages [PDF]

, 2009
Primordial molecules were formed during the Dark Ages, i.e. the time between recombination and reionization in the early Universe. The purpose of this article is to analyze the formation of primordial molecules based on heavy elements during the Dark ...
Abel, Abel, Affleck, Applegate, Barkana, Basu, Basu, Bromm, Burles, C. Winteler, Ciardi, Cyburt, D. Puy, Dolgov, Dubrovich, Dunkley, Fall, Fendt, Field, Flower, Flower, Galli, Glover, Glover, Glover, Harwit, Hindmarsh, Hirata, Huntress, Jedamzik, Khlopov, Komatsu, Kompaneets, Le Bourlot, Lepp, Lepp, Lipovka, M. Signore, Maio, Malaney, Maoli, Maoli, Matsuura, Matsuura, Matsuura, McGreer, Molaro, Nagakura, Omukai, Omukai, P. Vonlanthen, Peebles, Peebles, Pfenniger, Puy, Puy, Puy, Puy, Puy, Péquignot, Rauscher, Ripamonti, Ripamonti, Saslaw, Schleicher, Shchekinov, Signore, Signore, Silk, Songaila, Songaila, Stancil, Stancil, Steigman, T. Rauscher, Tegmark, Uehara, Uehara, V. Dubrovich, Verner, Verner, Woodall, Yoshida   +82 more
core   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Missing-linker metal-organic frameworks for oxygen evolution reaction

Nature Communications, 2019
While water splitting electrocatalysis provides a means to store electrical energy as fuel, the water oxidation catalysts typically show low performances.
Ziqian Xue, Kang Liu, Qinglin Liu, Yinle Li, Manrong Li, Cheng-Yong Su, Naoki Ogiwara, Hirokazu Kobayashi, Hiroshi Kitagawa, Min Liu, Guangqin Li   +10 more
doaj   +1 more source

Coffee waste-derived porous carbon for hydrogen and oxygen evolution reaction

Chemical Physics Impact, 2023
Porous carbon was synthesized from coffee waste for hydrogen evolution reaction (HER) and oxygen evolution reaction (OER). The coffee waste was carbonized at 600 °C for 2 hrs and activated at 500, 600, and 700 °C, respectively. The activated coffee waste
Keshab Pandey, Hae Kyung Jeong
doaj   +1 more source