Results 191 to 200 of about 96,355 (316)

Preemptive Propofol Administration in Spinal Cord Injury: Effects on Pain‐Induced Hypertension, Neuroinflammation, and Functional Recovery in Rats

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Spinal cord injury (SCI) triggers secondary damage, including pain‐induced hypertension, inflammation, and hemorrhage, impairing recovery. This study evaluated the efficacy of general anesthesia with preemptive propofol administration in mitigating secondary damage in SCI rats. SCI was induced in rats using a contusion model.
Qun Cheng   +2 more
wiley   +1 more source

Relaxin‐2 Ameliorates Spinal Cord Injury by Inhibiting Microglia Activation

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aims to assess the therapeutic effectiveness of Relaxin‐2 (RLN‐2) in promoting functional recovery and neuroprotection following spinal cord injury (SCI) in mice. Furthermore, continuous subcutaneous infusion of Serelaxin (0.5 mg/kg/day; human recombinant relaxin‐2) improved neurological recovery, as evidenced by higher Basso ...
Ji‐Huan Wang   +2 more
wiley   +1 more source

Safety Assessment of a 1940 nm Tm:YAP Laser for Fractional Skin Ablation in a Swine Model

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives This exploratory study was aimed to evaluate the safety and preliminary efficacy of Epicare, a 1940 nm thulium‐doped yttrium aluminum perovskite (Tm:YAP) laser, for fractional skin ablation in a swine model. The goal was to assess collagen remodeling and tissue responses across varied laser settings to optimize skin resurfacing ...
Yuval Ramot   +7 more
wiley   +1 more source

Development of a Decellularized Urinary Bladder Matrix and Heparin‐Based Cryogel for Promoting Angiogenesis

open access: yesMacromolecular Bioscience, EarlyView.
A dECM‐based cryogel scaffold with sustained VEGF release is developed to promote angiogenesis in ischemic tissues. Fabricated from decellularized porcine urinary bladder matrix and heparin, the scaffold supports VEGF binding and prolonged release. The cryogel demonstrates enhanced angiogenic potential in vitro and in a murine hindlimb ischemia model ...
Dayeon Roo   +7 more
wiley   +1 more source

Optimizing Electrospun PVA Fibers with MXene Integration for Biomedical Applications

open access: yesMacromolecular Materials and Engineering, EarlyView.
MXene flakes embedded in PVA electrospun fibers improve mechanical stiffness and electro‐conductive properties, not negatively influencing the in vitro viability of L929 cells. These findings suggest the promising use of MXene‐loaded nanofibers as innovative and highly versatile platforms for tissue engineering and biosensing applications.
Nergis Zeynep Renkler   +10 more
wiley   +1 more source

Automated versus manual oxygen titration in COPD exacerbation: machine or hands, this is the question

open access: yesInternational Journal of COPD, 2017
Gulsah Karaoren,1 Senay Goksu Tomruk,1 Antonio M Esquinas2 1Department of Anesthesiology and Reanimation, Istanbul Umraniye Research Hospital, Istanbul, Turkey; 2Intensive Care Unit, Hospital Morales Meseguer, Murcia, Spain We have read the article
Karaoren G, Goksu Tomruk S, Esquinas AM
doaj  

Poly(amino acid) Synthesis from 2,5‐Diketopiperazines for Acid‐Actuated Drug Release

open access: yesMacromolecular Materials and Engineering, EarlyView.
The ring‐opening polymerization (ROP) of 2,5‐diketopiperazines (2,5‐DKPs) to yield poly(amino acids) is reported. This route to poly(amino acids) has circularity, and permits the straightforward production of nanoparticles for controlled release applications.
Patrick A. Wall   +3 more
wiley   +1 more source

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