Results 211 to 220 of about 187,990 (300)

Hydrogen: an advanced and safest gas option for cancer treatment. [PDF]

Med Gas Res
Gupta N, Abd El-Gawaad NS, Mallasiy LO, Alghamdi S, Yadav VK.   +4 more
europepmc   +1 more source

Diesel Aspiration Pneumonitis: A Rare but Serious Occupational Hazard. [PDF]

Cureus
Alwesaibi HA, Albin Saad AH, Almulaify MS, Alqatari MG.   +3 more
europepmc   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

Acute exogenous lipoid pneumonia leading to severe ARDS: a case report. [PDF]

BMC Pulm Med
Ye Y, Cai H, Dai C, Hu Q, Cao Q, Bi J, Song Y, Jiang J, Chen S.   +8 more
europepmc   +1 more source

Cerebellar defects are a primary pathology in mouse models of spinal muscular atrophy

Brain Pathology, EarlyView.
Purkinje cell (PC) degeneration is localized to posterior lobules in the cerebellum, and rescue of survival motor neuron protein expression levels in motor neurons does not ameliorate this effect. Representative images of sagittal cerebellar sections stained with anti‐calbindin in the vermis and hemisphere at P12 for wild type, ChATCre+ rescue (Rescue),
Nicholas C. Cottam, Morgan Dowling, Lingling Kong, Michelle Harran Chan‐Cortés, Christine J. Charvet, Naika Norzeron, Cameron Grover, Melissa A. Harrington, Charlotte J. Sumner, Jianli Sun   +9 more
wiley   +1 more source

Long-term outcomes in five patients with autoimmune pulmonary alveolar proteinosis treated with molgramostim inhalation solution. [PDF]

ERJ Open Res
Montaño C, Bendstrup E, Rønnov-Jessen I, Salgado S, Sterniste G, Valipour A, Veltkamp M, Molina-Molina M.   +7 more
europepmc   +1 more source

Addressing treatable traits in bronchiectasis through non-pharmacological therapies: a narrative review. [PDF]

J Thorac Dis
Lee AL, Spinou A, Basavaraj A.
europepmc   +1 more source

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye, Claire Pearson, Tibyan Babiker, Emilio Agostinelli, Rumaitha Al‐Hosni, Paolo Tammaro   +5 more
wiley   +1 more source

Exogenous GM-CSF therapy for autoimmune pulmonary alveolar proteinosis: a systematic literature review. [PDF]

Front Med (Lausanne)
Chen W, Feng X, Yao LK, Li X, Yang ZM, Qin XY, Li Y, Qiu Y.   +7 more
europepmc   +1 more source

Pharmacological evaluation of non‐nucleotide purine derivatives as P2X7 antagonists for the treatment of neuroinflammation in traumatic brain injury

British Journal of Pharmacology, EarlyView.
Background and purpose Traumatic brain injury (TBI) is considered to be a leading cause of mortality and disability worldwide. After TBI, innate immunity is rapidly activated in response to damage‐associated molecular patterns, such as ATP release, recognised by P2X7 receptors.
Inés Valencia, Andrea Pastor‐Martínez, Céline Decouty‐Pérez, Ana Belen Lopez‐Rodriguez, María Álvarez‐Rubal, Eva Ramos, Francesco Calzaferri, Jorge Zamorano‐Fernández, Javier Giner‐García, Alexis J. Palpán‐Flores, Víctor Rodríguez‐Domínguez, Javier Rodríguez de Cía, Borja J. Hernández‐García, Alejandro Romero, Cristóbal de los Ríos, Javier Egea   +15 more
wiley   +1 more source