Results 221 to 230 of about 57,040 (314)

Modeling fire‐related smoke inhalation injury using the human lung‐on‐a‐chip and organoid platform: Pathogenesis insights and therapeutic evaluation

open access: yesVIEW, EarlyView.
Fire‐related smoke inhalation‐induced acute lung injury (SI‐ALI) poses a significant public health risk, yet effective treatments are limited due to the lack of suitable models. This study developed a more realistic model of SI‐ALI using organ‐on‐a‐chip and organoid technologies, identified key molecules such as catechol‐O‐methyltransferase and ...
Junmin Li   +12 more
wiley   +1 more source

Reply to the comment by Sakamoto et al. on "The method to identify invasive mechanical ventilation with Japanese claim data". [PDF]

open access: yesJ Intensive Care
Ohbe H   +8 more
europepmc   +1 more source

Semaglutide to remodel mitochondrial dynamics and mitophagy balance for vascular dementia therapy

open access: yesVIEW, EarlyView.
The effects of semaglutide on IR, mitochondrial dynamics, and mitophagy in the hippocampus of BCAS mice after CCH. It was shown that semaglutide maintained the balance of mitochondrial dynamics and mitophagy by improving IR and passing through GLP‐1R/PI3K/Akt pathway, reduced hippocampal neuroinflammation and neuron loss, and thus promoted the recovery
Xiaoyan Yang   +11 more
wiley   +1 more source

Upper airway obstruction due to aspiration of the tamponading gauze swab placed following severe blood loss during sinus flap surgery in a Shetland pony (Equus caballus)

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 24‐year‐old pony, weighing 130 kg, was presented with chronic sinusitis despite previous tooth extraction and sinus trephination in standing sedation. General anaesthesia was induced for a maxillary sinus flap. Severe haemorrhage occurred, which required tamponade of the sinus using a gauze swab.
Vanessa Heitzmann   +2 more
wiley   +1 more source

Transcriptional Heterogeneity and Differential Response of Rod Photoreceptor Pathway Uncovered by Single‐Cell RNA Sequencing of the Aging Mouse Retina

open access: yesAging Cell, EarlyView.
Healthy aging is accompanied by transcriptional dysregulation in retinal cells, leading to alterations in key molecular pathways and cellular responses, with the scotopic pathway being particularly affected. We show that rod photoreceptors, essential for initiating scotopic (low‐light) vision, exhibit selective vulnerability to aging‐associated ...
Laura Campello   +5 more
wiley   +1 more source

A Curious Case of Purple Chromaturia. [PDF]

open access: yesCureus
Dhakal R   +4 more
europepmc   +1 more source

Muscle Mitochondrial Respiration and Cardiorespiratory Fitness Contribute to Slower Walking Speed of Older Individuals Who Identify as Black

open access: yesAging Cell, EarlyView.
While the etiology of race differences in mobility is multifactorial, our data indicate that muscle mitochondrial respiration and cardiorespiratory fitness may contribute to the slower walking speed of individuals who identify as Black compared to White.
Paul M. Coen   +12 more
wiley   +1 more source

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