Results 151 to 160 of about 4,052,823 (334)

(Table 1) Oxygen and iron isotope ratios of Kaalvallei and Bellsbank eclogite xenoliths

open access: yes, 2009
(Table 1) Oxygen and iron isotope ratios of Kaalvallei and Bellsbank eclogite ...
Alt, Jeffrey C   +19 more
core   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan   +14 more
wiley   +1 more source

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

open access: yesAdvanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim   +12 more
wiley   +1 more source

Neutron Depth Profiling: The Core Link Connecting the Microscopic Mechanisms of Lithium‐Ion Batteries With Intelligent Design

open access: yesAdvanced Science, EarlyView.
Neutron depth profiling exploits the 6Li(n,3H)4He reaction to provide quantitative, isotope‐specific, depth‐resolved maps of lithium inside operating lithium‐ion batteries, directly linking lithium transport, dendrite growth and interfacial short‐circuiting to a physics‐informed machine‐learning roadmap that turns this non‐destructive operando ...
Yulong Zhang   +8 more
wiley   +1 more source

A Contiguous Taltson‐Thelon Margin Revisited

open access: yesGeochemistry, Geophysics, Geosystems
The amalgamation of Laurentia was initiated along the western margin of the Rae craton. However, the tectonic setting that generated magmatic rocks along this margin has long been debated, with the Thelon tectonic zone in the north having formed in an ...
J. A. Cutts   +8 more
doaj   +1 more source

Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen   +12 more
wiley   +1 more source

Tip60‐Mediated USP22 Lactylation Drives Glutamine Metabolic Reprogramming via SLC25A5 in TNBC

open access: yesAdvanced Science, EarlyView.
Tip60‐mediated USP22 K134 lactylation, stabilizing SLC25A5 to enhance glutamine metabolism and α‐KG secretion. The secreted α‐KG drives GPR91‐dependent M2 macrophage polarization, promoting triple‐negative breast cancer progression. Targeting this axis synergizes with CB‐839, offering a promising therapeutic strategy for TNBC.
Fang Zhen   +7 more
wiley   +1 more source

Overcoming the *H‐NOx Coupling Bottleneck via Palladium‐Enabled Relay Catalysis on CuCo2O4 Toward Ampere‐Level Nitrate‐to‐Ammonia

open access: yesAdvanced Science, EarlyView.
Pd‐doped hollow spiny CuCo2O4 microspheres deliver ampere‐level electrocatalytic nitrate to ammonia. Cu and Co sites undergo relay catalysis for sequential nitrate reduction, while Pd accelerates water dissociation to supply abundant active hydrogen (*H).
Yuhuan Cui   +8 more
wiley   +1 more source

Electrocatalytic Urea Synthesis From CO2 and N2/NO3−: Bridging Catalyst Activity, C–N Coupling Kinetics, and Industrial Applicability

open access: yesAdvanced Science, EarlyView.
This review compares NO3− + CO2 and N2 + CO2 electrocatalytic urea synthesis in feedstock properties, catalyst design, C–N coupling mechanisms, performance optimization, and engineering applicability. The two systems correspond to a near‐term deployable route and a long‐term green synthesis goal, respectively.
Fulin Dong   +5 more
wiley   +1 more source

Stabilizing Oxygen Redox via Li Dopants Into P2‐Type Cathodes for High‐Voltage Sodium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
Regulating anionic redox of layered cathodes provides the promises as performance promotor for sodium ion batteries. In this work, Li doping strategy has been developed to stabilize oxygen redox in the voltage window from 4.1 to 4.3 V. The underlying mechanism has been investigated through integrating a variety of characterizations.
Peng Dai   +19 more
wiley   +1 more source

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