Results 71 to 80 of about 10,509,509 (258)

Spatial oxygen heterogeneity in a Hediste diversicolor irrigated burrow [PDF]

, 2011
The heterogeneity of oxygen distribution in a Hediste diversicolor burrow environment was investigated in a laboratory experiment using a 6-mm thick tank equipped with oxygen planar optodes. The twodimensional oxygen distribution in a complete burrow was
Franck Gilbert, Poggiale, Jean-Christophe, Cuny, Philippe, Esteves, José Luis, Philippe Cuny, José Luis Esteves, Gilbert, Franck, Laura Pischedda, Jean-Christophe Poggiale, Pischedda, Laura, Esteves, Josã© Luis, Poggiale, Jean Christophe   +11 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Fluorescent sensing of reactive oxygen species on the sub-cellular level

Redox Experimental Medicine
While reactive oxygen species are known to play many critical roles in health and disease, it is their sub-cellular localisation that ultimately determines their cellular impact.
Aedena-Raquel Remy, Joy B Ghrayche, Elizabeth J New   +2 more
doaj   +1 more source

Rising levels of atmospheric oxygen and evolution of Nrf2 [PDF]

Scientific Reports, 2016
AbstractIn mammals, the master transcription regulator of antioxidant defences is provided by the Nrf2 protein. Phylogenetic analyses of Nrf2 sequences are used here to derive a molecular clock that manifests persuasive evidence that Nrf2 orthologues emerged and then diverged, at two time points that correlate with well-established geochemical and ...
Gacesa, Ranko, Dunlap, Walter C., Barlow, David J., Laskowski, Roman A., Long, Paul F.   +4 more
openaire   +4 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The self-referencing oxygen-selective microelectrode: Detection of transmembrane oxygen flux from single cells

, 1999
A self-referencing, polarographic, oxygen-selective microelectrode was developed for measuring oxygen fluxes from single cells. This technique is based on the translational movement of the microelectrode at a known frequency through an oxygen gradient ...
Porterfield, D.M., Smith, P.J., Sanger, R.H., Smith, P. J. S., Sanger, R. H., Porterfield, D. M., Land, S. C.; id_orcid, Land, S.C.   +7 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Wisconsin Oxygen/Hydrogen Company, Kenosha, Wisconsin 1920-1925

, 1920
It wasn’t long before the Brant Brothers expanded their entrepreneurial efforts to Kenosha, Wisconsin, where they built a second electrolytic oxygen/hydrogen plant, known as Wisconsin Oxygen/Hydrogen Company.

core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source