Results 81 to 90 of about 5,141,564 (262)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Effect of Tin Precursor Ligand in SnFe–N–C Single‐Site Catalysts for Oxygen Reduction Reaction

open access: yesChemElectroChem
Iron–nitrogen–carbon materials are still the most promising alternative to platinum group materials for the electrochemical reduction of O2. Doping with a secondary metal center is a possible way to further enhance the activity, and Sn seems to be a ...
Marco Mazzucato   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Facile modulation of hierarchical structures in biomass-derived carbon via metal–organic framework-mediated assembly for enhanced oxygen and carbon dioxide reduction reactions

open access: yesNano Research
Rationally modulating the hierarchical structure of biomass-derived carbon while ensuring developed pore structure and effective doping is imperative for its high-value utilization, but remains challenging.
Junjie Zhang   +10 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Template-free ultraspray pyrolysis synthesis of N- and Fe-doped carbon microspheres for oxygen reduction electrocatalysis

open access: yes, 2015
The overall energy efficiency in fuel cells is deeply affected by the sluggish kinetics of the two electrodes processes. Between them the most kinetically hindered is the oxygen reduction reaction (ORR) at the cathode.
J. Ding   +4 more
core   +2 more sources

The oxygen adsorption and oxygen reduction reaction mechanism on nitrogen doped graphene: a first-principles study

open access: yes, 2010
The oxygen adsorption and oxygen reduction reaction mechanism on nitrogen doped graphene: a first-principles ...
包信和   +4 more
core   +1 more source

A primer on electrocatalysis [PDF]

open access: yesJournal of the Serbian Chemical Society, 2005
A short review of the development and achievement of electrocatalysis in the last 50 years is given. The need for the knowledge of the reactionmechanism and position of the rate determining step for rational choice of catalyst is particularly stressed ...
J.O’M. BOCKRIS
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy