Results 81 to 90 of about 1,091,496 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Carbon nanotubes as a 1D template for the synthesis of air sensitive materials: about the confinement effect [PDF]

, 2005
Cobalt ferrite and cobalt iron nanowires with an average diameter of 50 nm and lengths up to several micrometers were synthesized inside multi-walled carbon nanotubes (MWNTs) under mild reaction conditions, i.e.
Estournès, Claude, Ledoux, Marc-Jacques, Leuvrey, Cédric, Pham-Huu, Cuong, Tessonnier, Jean-Philippe, Winé, Gauthier   +5 more
core   +2 more sources

Rational Design of Covalent Organic Frameworks-Based Single Atom Catalysts for Oxygen Evolution Reaction and Oxygen Reduction Reaction

Molecules
The rational design of high-performance catalysts for the oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) is essential for the development of clean and renewable energy technologies, particularly in fuel cells and metal-air batteries.
Wenli Xie, Bin Cui, Desheng Liu, Haicai Huang, Chuanlu Yang   +4 more
doaj   +1 more source

New Progress on Development of Oxygen Evolution Reaction Catalysts

Journal of MMIJ, 2017
In recent years, the electrochemical water splitting using renewable energy has attracted considerable attention for the production and utilization of hydrogen gas as a fuel. However, the high overpotential for the oxygen evolution reaction increases the
Shunsuke YAGI, Hidekazu IKENO, Ikuya YAMADA   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Characterization of Pd Nanocomposites for the Oxygen-Reduction Reaction

Proceedings
Carbon nanocomposites are essential supports in fuel cell catalysts, ensuring dispersion, anchoring, and reactant access. Here, we demonstrated an in situ synthesis of Pd nanoparticles using electrogenerated hydrophilic carbon (EHC) matrix that acts ...
Ilias Ouanzi, Maria C. Oliveira
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Promotion of oxygen reduction by a bio-inspired tethered iron phthalocyanine carbon nanotube-based catalyst [PDF]

, 2014
Electrocatalysts for oxygen reduction are a critical component that may dramatically enhance the performance of fuel cells and metal-air batteries, which may provide the power for future electric vehicles.
AA Gewirth, AA Tanaka, C Bezerra, CJ Chang, F Jaouen, F Jaouen, Fdr Jaouen, G Wu, H Meier, H Michel, J Greeley, J Suntivich, JL Bahr, JP Collman, K Gong, K Sasaki, KM Kadish, M Lefèvre, M Lefèvre, MK Debe, R Cao, R Chen, R Jasinski, S Gupta, S Rywkin, SNS Goubert-Renaudin, UI Koslowski, UI Kramm, VR Stamenkovic, W Li, X Li, Y Liang, Y Liang, Z Chen, Z Shi, Z-S Wu   +35 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source