Results 101 to 110 of about 1,091,496 (304)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Metal-free carbon-nitrogen@carbon-type hybrid electrocatalysts for peroxide-producing oxygen reduction reaction

Carbon Future
Hydrogen peroxide (H2O2) is a widely utilized chemical in environmental cleaning, medical disinfection, and chemical engineering. Compared to the traditional anthraquinone oxidation method, the electrocatalytic oxygen reduction reaction (ORR) has become ...
Bin Wu, Dulce M. Morales, Mingren Liu, Dongjiu Xie, Ping Feng, Yan Lu, Marcel Risch, Martin Oschatz, Tristan Petit   +8 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

First principles studies of the size and shape effects on reactivity of the Se modified Ru nanoparticles

, 2012
We present here the results of our density-functional-theory-based calculations of the electronic and geometric structures and energetics of Se and O adsorption on Ru 93- and 105-atom nanoparticles. These studies have been inspired by the fact that Se/Ru
Stolbov, Sergey, Zuluaga, Sebastian
core   +1 more source

Enhanced oxygen reduction reaction on caffeine-modified platinum single-crystal electrodes

Communications Chemistry
Enhancing the activity of the oxygen reduction reaction (ORR) is crucial for fuel cell development, and hydrophobic species are known to increase the ORR activity.
Nagahiro Hoshi, Masashi Nakamura, Ryuta Kubo, Rui Suzuki   +3 more
doaj   +1 more source

Two-dimensional circular platinum nanodendrites toward efficient oxygen reduction reaction and methanol oxidation reaction

Electrochemistry Communications, 2019
Two-dimensional circular platinum nanodendrites (~13 nm thick, up to 138.8 nm in diameter) were synthesized by chemical reduction of platinum complexes with ascorbic acid in the presence of block copolymer and pre-formed seeds.
Huiyuan Liu, Jiaqi Qin, Siqin Zhao, Zhanming Gao, Qiang Fu, Yujiang Song   +5 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Mass-transport resistances of acid and alkaline ionomer layers: A microelectrode study part 1 - Microelectrode development [PDF]

, 2019
The use of microelectrodes to study localized mass-transport phenomena in fuel-cell catalyst layers is an increasingly valuable tool. However, existing microelectrode cells have been used in static, equilibrated environment modes with poorly controlled ...
Danilovic, N, Kushner, DI, Petrovick, JG, Radke, CJ, Tesfaye, M, Weber, AZ   +5 more
core  

Porphyrin-based frameworks and derivatives for the oxygen reduction reaction

Materials Today Catalysis
The global energy crisis and environmental pollution issues caused by the continuous consumption of fossil fuels are increasingly becoming severe. Developing clean and sustainable hydrogen (H2) energy and corresponding storage and conversion devices have
Yiwen Cao, Yonghong Mou, Jieling Zhang, Rui Zhang, Zuozhong Liang   +4 more
doaj   +1 more source