Results 91 to 100 of about 7,002,510 (397)

Acute Low-Dose Hyperoxia during a Single Bout of High-Intensity Interval Exercise Does Not Affect Red Blood Cell Deformability and Muscle Oxygenation in Trained Men—A Randomized Crossover Study

Sports, 2020
Recent technological developments provide easy access to use an artificial oxygen supply (hyperoxia) during exercise training. The aim of this study was to assess the efficacy of a commercially available oxygen compressor inducing low-dose hyperoxia, on ...
Nils Freitag, Tim Böttrich, Pia D. Weber, Giorgio Manferdelli, Daniel A. Bizjak, Marijke Grau, Tanja C. Sanders, Wilhelm Bloch, Moritz Schumann   +8 more
doaj   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy

European Respiratory Journal, 2018
A possible precision-medicine approach to treating obstructive sleep apnoea (OSA) involves targeting ventilatory instability (elevated loop gain) using supplemental inspired oxygen in selected patients.
S. Sands, B. Edwards, P. Terrill, J. Butler, R. Owens, L. Taranto-Montemurro, A. Azarbarzin, M. Marques, L. Hess, E. Smales, C. D. de Melo, D. White, A. Malhotra, A. Wellman   +13 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Commentary: Ozone therapy as a novel complementary therapeutic approach in refractory idiopathic granulomatous mastitis

Frontiers in Medicine, 2023
Salvatore Chirumbolo, Marianno Franzini, Sergio Pandolfi, Umberto Tirelli, Luigi Valdenassi   +4 more
doaj   +1 more source

ALGORITHM FOR THE TREATMENT OF PATIENTS WITH ACUTE HEART FAILURE

Архивъ внутренней медицины, 2018
Acute heart failure (AHF) and acute decompensation of chronic heart failure (ADHF) are urgent health problems. The main tasks of the managing the patients with these conditions include the achieving of optimal and stable resolution of edema and dyspnea ...
E. V. Reznik, Yu. V. Gavrilov, I. G. Nikitin   +2 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The Effects of the Pericapsular Nerve Group Block on Postoperative Pain in Patients with Hip Fracture: A Multicenter Study

Diagnostics
Background: An adequate early mobilization followed by an effective and pain-free rehabilitation are critical for clinical and functional recovery after hip and proximal femur fracture.
Carmine Iacovazzo, Rosario Sara, Pasquale Buonanno, Maria Vargas, Antonio Coviello, Roberta Punzo, Vincenzo Maffei, Annachiara Marra   +7 more
doaj   +1 more source

Oxygen therapy for interstitial lung disease: a systematic review

European Respiratory Review, 2017
This review aims to establish the impact of oxygen therapy on dyspnoea, health-related quality of life (HRQoL), exercise capacity and mortality in interstitial lung disease (ILD).
Emily C Bell, N. Cox, N. Goh, I. Glaspole, G. Westall, Alice L. Watson, A. Holland   +6 more
semanticscholar   +1 more source

Hyperbaric Oxygen Therapy: Effect on Wound Healing and Traumatic Brain Injuries

, 2019
Hyperbaric Oxygen Therapy is a new form of treatment being used to heal and help improve symptoms of traumatic brain injuries, external wounds, and strokes. HBOT helps to completely saturate hemoglobin with oxygen, which then allows for a larger capacity
Seuffert, Sara L.
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