Results 41 to 50 of about 1,069,118 (347)

Avoiding Routine Oxygen Therapy in Patients With Myocardial Infarction Saves Significant Expenditure for the Health Care System—Insights From the Randomized DETO2X-AMI Trial

open access: yesFrontiers in Public Health, 2022
Background: Myocardial infarction (MI) occurs frequently and requires considerable health care resources. It is important to ensure that the treatments which are provided are both clinically effective and economically justifiable.
Robin Hofmann   +15 more
doaj   +1 more source

Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]

open access: yes, 2016
Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A.   +3 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Hyperbaric oxygen therapy services at the Pamela Youde Nethersole Eastern Hospital hyperbaric oxygen therapy Center: A retrospective epidemiological study

open access: yesHong Kong Journal of Emergency Medicine
Introduction The aim of this retrospective epidemiological study is to analyze the characteristics and caseload of patients treated at the Pamela Youde Nethersole Eastern Hospital (PYNEH) hyperbaric oxygen therapy (HBOT) Center in Hong Kong from 2018 to ...
Kin Bong Tang   +2 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector. [PDF]

open access: yes, 2010
One of the major hurdles for the development of gene therapy for Fanconi anemia (FA) is the increased sensitivity of FA stem cells to free radical-induced DNA damage during ex vivo culture and manipulation.
Adair, J   +10 more
core   +2 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

From skeletal muscle to stem cells: an innovative and minimally-invasive process for multiple species

open access: yesScientific Reports, 2017
Bone marrow and adipose tissue represent the two most commonly exploited sources of adult mesenchymal stem cells for musculoskeletal applications.
J. Ceusters   +5 more
doaj   +1 more source

Investigation of robotics-assisted tilt-table therapy for early-stage rehabilitation in spinal cord injury [PDF]

open access: yes, 2013
This article provides the outcome of an investigation of robotics-assisted tilt-table therapy for early-stage rehabilitation in spinal cord ...
Allan, David   +4 more
core   +1 more source

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