Results 41 to 50 of about 7,143,446 (406)

Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells [PDF]

open access: yes, 2016
Indexación: Web of ScienceTumor angiogenesis is widely recognized as one of the hallmarks of cancer. Consequently, during the last decades the development and testing of commercial angiogenic inhibitors has been a central focus for both basic and ...
Carrasco-Avino, G   +4 more
core   +1 more source

Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX)

open access: yesIntensive Care Medicine, 2019
Purpose Sepsis is a common reason for intensive care unit (ICU) admission and mortality in ICU patients. Despite increasing interest in treatment strategies limiting oxygen exposure in ICU patients, no trials have compared conservative vs.
P. Young   +14 more
semanticscholar   +1 more source

Home Oxygen Therapy for Children. An Official American Thoracic Society Clinical Practice Guideline

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2019
Background: Home oxygen therapy is often required in children with chronic respiratory conditions. This document provides an evidence‐based clinical practice guideline on the implementation, monitoring, and discontinuation of home oxygen therapy for the ...
D. Hayes   +21 more
semanticscholar   +1 more source

Carbon monoxide poisoning. Causes, diagnosis, clinical manifestations and principles of treatment

open access: yesМедицина неотложных состояний, 2022
The article considers the causes of carbon monoxide poisoning, the main symptoms of mild, moderate, and severe poisoning. The article describes the pathophysiology of poisoning, the effect of carboxyhemoglobin on various organs and systems of the victim ...
S.M. Nedashkivskyi   +3 more
doaj   +1 more source

Emergency management of cyanotic spell in a COVID-19 suspect tetralogy of Fallot child

open access: yesBali Journal of Anesthesiology, 2021
The novel coronavirus (SARS-CoV-2) is suggested to increase the risk of morbidity and mortality in patients with underlying cardiac and pulmonary disorders.
Rohan Magoon   +3 more
doaj   +1 more source

Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]

open access: yes, 2016
Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A.   +3 more
core   +2 more sources

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Imatinib-induced interstitial pneumonitis – a literature review and case report [PDF]

open access: yes, 2020
Imatinib is generally well tolerated, with mild common side effects such as nausea and vomiting, diarrhea, muscle cramps, fatigue, skin rash and edema; however, pulmonary complications are uncommon. A 73-year-old woman undergoing one month treatment with
Ciulei, George   +12 more
core   +2 more sources

Antimicrobial use of reactive oxygen therapy: current insights

open access: yesInfection and Drug Resistance, 2018
Infections caused by drug-resistant pathogens are a global public health problem. The introduction of a new antimicrobial strategy is an unavoidable option for the management of drug-resistant pathogens.
M. Y. Memar   +3 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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