Results 61 to 70 of about 654,751 (265)
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Hyperbaric oxygen therapy after failure of conventional therapy for sudden deafness
Hyperbaric oxygen after failure of conventional therapy for sudden deafness. Problems/objectives: We investigated the effect of secondary hyperbaric oxygen therapy (HBO) for patients with idiopathic sudden sensorineural hearing loss after unsuccessful ...
C. Desloovere, R. Knecht, P. Germonpré
doaj +2 more sources
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
The Effectiveness of Hyperbaric Oxygen Therapy in an Established Intracerebral Tumor Model
Objective:Gliomas are the most common brain tumor in adults. Tumor-related endothelial cells are of neoplastic nature and have malignant properties such as proliferation and invasion.
Tolga Turan DÜNDAR +4 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Ozone adjunct treatment in facing multidrug‐resistant bacteria?
Salvatore Chirumbolo +2 more
doaj +1 more source
Background: An adequate early mobilization followed by an effective and pain-free rehabilitation are critical for clinical and functional recovery after hip and proximal femur fracture.
Carmine Iacovazzo +7 more
doaj +1 more source
ALGORITHM FOR THE TREATMENT OF PATIENTS WITH ACUTE HEART FAILURE
Acute heart failure (AHF) and acute decompensation of chronic heart failure (ADHF) are urgent health problems. The main tasks of the managing the patients with these conditions include the achieving of optimal and stable resolution of edema and dyspnea ...
E. V. Reznik +2 more
doaj +1 more source
Clinical applications for the use of oxygen have extended beyond the hospital setting to home therapy. In patients with hypoxemic chronic obstructive pulmonary disease, long-term administration of oxygen has been substantiated as beneficial in terms of improved survival, decreased hospitalization, increased exercise capability and endurance, enhanced ...
openaire +2 more sources

