Results 41 to 50 of about 4,326,665 (258)

The Translational Medicine Regarding Ozone in Saline Solutions. Comment on Armeli et al. Ozone Saline Solution Polarizes Microglial Cells Towards an Anti-Inflammatory Phenotype. Molecules 2025, 30, 3932

Molecules
This commentary critically evaluates the translational relevance of a recent study investigating the effects of ozonated saline solution (O3SS) on microglial and endothelial cell models. While the original research proposes potential antioxidant and anti-
Marianno Franzini, Luigi Valdenassi, Salvatore Chirumbolo   +2 more
doaj   +1 more source

Oxygen-Loaded Lipid Nanobubbles for Biofilm Eradication by Combined Trimodal Treatment of Oxygen, Silver, and Photodynamic Therapy

, 2023
The hypoxic microenvironment of bacterial biofilms is one of the main causes of their recalcitrance. The combined therapy of photodynamic therapy (PDT) and silver nanoparticles (AgNPs) has shown its potential for biofilm eradication. However, hypoxia can
Lingyu Ye (12693074), Lulu Yang, Lingyu Ye, Lingzhi Zhao, Ying Liu, Ying Liu (18461), Pingwei Yang (16426794), Lingzhi Zhao (1551874), Xinyi Tan, Yunyun Zhou, Juanjuan Peng (1602547), Yunyun Zhou (1780960), Pingwei Yang, Xinyi Tan (1983526), Juanjuan Peng, Lulu Yang (1728349)   +15 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Influence of Adjuvant Hyperbaric Oxygen Therapy on Short-term Complications During Surgical Reconstruction of Upper and Lower Extremity War Injuries: Retrospective Cohort Study [PDF]

, 2008
Cilj Odrediti utjecaj liječenja hiperbaričnom oksigenacijom (HBO) na kratkoročne komplikacije složenih ratnih ozljeda gornjih i donjih udova u ranjenika koji su bili i koji nisu bili liječeni u skladu s kirurškom strategijom Organizacije Sjeverno ...
Petričević, Ante, Čapkun, Vesna, Roje, Željka, Eterović, Davor, Roje, Tinka, Roje, Zdravko, Družijanić, Nikica   +6 more
core   +1 more source

Oxygen-Generating Hydrogels Overcome Tumor Hypoxia to Enhance Photodynamic/Gas Synergistic Therapy

, 2022
Hypoxic environment is a bottleneck of photodynamic therapy (PDT) in tumor treatment, as oxygen is the critical substrate for photosensitivity reaction.
Yinghua Mao (11519785), Juan Xu (225010), Shu Rong (225068), Yuhang He (6185693), Mi Zhang (42795), Xuemei Jia (9226116), Xiaoguang Liu (109982), Feng Zheng (91182), Yonghong Chen (141184), Hong Li (20183), Weilong Tan (6536006)   +10 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Effect of hyperbaric oxygen therapy on peripheral blood inflammatory markers in patients with neuromyelitis optica spectrum disorder: a retrospective cohort study

Frontiers in Neurology
BackgroundNeuromyelitis optica spectrum disorder (NMOSD), an AQP4-IgG-mediated central nervous system demyelinating disease, is prone to recurrent disability.
Liya Pan, Liya Pan, Yanming Mo, Yulan Wei, Shisheng Luo, Yuan Wu   +5 more
doaj   +1 more source

EIF3J-AS1 promotes glioma cell growth via up-regulating ANXA11 through sponging miR-1343-3p

Cancer Cell International, 2020
Background Glioma is one prevalent malignant tumor originates from the central nervous system. Dysregulation of long non-coding RNAs (lncRNAs) has been found to be a molecular signature behind the pathology of a variety of cancers, including glioma ...
Jianguo Qi, Zhengrui Wang, Zhensheng Zhao, Lijun Liu   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source