Results 121 to 130 of about 13,927 (251)
Phytotherapy Research, EarlyView.ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley +1 more source
Crystal structure of RohS, a heme-oxygenase-like N-oxygenase from azomycin biosynthesis. [PDF]
J Biol ChemWei ZW, Salamon P, Higgins MA, Ryan KS.
europepmc +1 more source
Phytotherapy Research, EarlyView.Neohesperidin alleviates doxorubicin‐induced cardiotoxicity by inhibiting METTL3‐mediated m6A modification of Nrf2 mRNA, thereby regulating Nrf2 and suppressing ferroptosis. ABSTRACT Doxorubicin (DOX) has antitumor efficacy, but its clinical application is restricted by multiple side effects, especially cardiotoxicity.
Ruijia Wen +9 more
wiley +1 more source
Heme Oxygenases: Novel Regulators of Reproductive Processes
Frontiers in Pharmacology, 2015 Ana Claudia Zenclussen +1 more
doaj +1 more source
Whole-Genome Sequence Dataset of <i>Rhodococcus qingshengii</i> IEGM 267-Terpenoid Biotransformer Toward Genetic Functional Annotation. [PDF]
MoleculesMaltseva PY +2 more
europepmc +1 more source
Phytotherapy Research, EarlyView.Rh1 attenuates oxidative stress and mitochondrial dysfunction through SIRT1‐related signaling. ABSTRACT Alzheimer's disease (AD) remains a progressive neurodegenerative disorder with limited therapeutic options. Ginsenoside Rh1 has been reported to possess neuroprotective properties, yet its specific role and underlying mechanisms in AD are not fully ...
Shi‐Lu Li +10 more
wiley +1 more source
The Factors Governing Metal Dependence of an Emergent Superfamily of Bimetallic Oxygenases. [PDF]
J Am Chem SocLiu C, Nguyen J, Britt RD, Rittle J.
europepmc +1 more source
Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases
Phytotherapy Research, EarlyView.Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin +7 more
wiley +1 more source
Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments
Smart Molecules, EarlyView.Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu +7 more
wiley +1 more source