Results 151 to 160 of about 63,041 (289)
Heme in Bacterial Pathogenesis and as an Antimicrobial Target. [PDF]
Chen PY, Skaar EP.
europepmc +1 more source
Using DNA metabarcoding, this study investigates pollen transported by syrphids (Syrphidae) in the Dolomiti Bellunesi National Park and agricultural sites in Northern Italy. The analysis reveals a high diversity of visited plant taxa, including previously undocumented plant–pollinator interactions.
Serena Magagnoli +6 more
wiley +1 more source
GCN2 in proteostasis: structural logic, signalling networks and disease
Threats to protein synthesis activate the kinase GCN2, initiating the integrated stress response (ISR). GCN2 is triggered by stalled ribosomes and uncharged tRNAs, which accumulate when amino acids are scarce. The ISR adjusts cellular physiology by promoting redox balance, protein quality control, and mitochondrial optimisation.
JiaYi Zhu, Stefan J. Marciniak
wiley +1 more source
Inhibition of Ring-Cleaving Dioxygenases by Natural Amino Acids. [PDF]
Wang Q, Li H, Gupta R.
europepmc +1 more source
θ‐CA3 from a marine diatom has an N‐terminal transmembrane helix and two homologous catalytic domains. The enzyme functions as a dimer, with active sites formed near the dimer interface. A bicarbonate ion binds on the symmetry axis of the dimer and forms hydrogen bonds with both monomers, thereby activating θ‐CA3 and tuning CO2 hydration activity ...
Hiroto Negoro +5 more
wiley +1 more source
Orthologue inference-based enzyme mining for diversification of the anti-cancer evodiamine scaffold. [PDF]
Kwan BD +6 more
europepmc +1 more source
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak +5 more
wiley +1 more source
Current Research Advances and Future Prospects on Microbial Consortia for Sustainable PFAS Remediation. [PDF]
Kareem HA, Khan MF.
europepmc +1 more source
Benign by design: A paradigm shift in cosmetic ingredient development
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota +3 more
wiley +1 more source

